Lowe G D, McKillop J H, Prentice A G
Postgrad Med J. 1979 Jan;55(639):18-21. doi: 10.1136/pgmj.55.639.18.
Eight cases are reported of extensive retroperitoneal haemorrhage in patients receiving anticoagulant therapy who subsequently died and underwent postmortem examination. No patient had an obvious source of bleeding, and in 5 cases no other cause for death was apparent. Three patients had had vascular surgical procedures: the other 5 were given anticoagulants for suspected venous thrombo-embolism. Six cases presented as unexpected circulatory collapse with rapid demise. Four patients had in addition gastro-intestinal bleeding of varying degree, with no obvious source. This acute massive type of retroperitoneal bleeding contrasts with the commoner presentations of pain, swelling, bruising and compression neuropathy: a high index of suspicion and urgent treatment are required if mortality is to be reduced.
报告了8例接受抗凝治疗的患者发生广泛腹膜后出血的病例，这些患者随后死亡并接受了尸检。没有患者有明显的出血源，5例患者没有其他明显的死亡原因。3例患者曾接受血管外科手术；另外5例因疑似静脉血栓栓塞而接受抗凝治疗。6例表现为意外的循环衰竭并迅速死亡。4例患者还伴有不同程度的胃肠道出血，且无明显出血源。这种急性大量腹膜后出血与更常见的疼痛、肿胀、瘀伤和压迫性神经病变表现形成对比：如果要降低死亡率，需要高度怀疑并进行紧急治疗。
