Suppr超能文献

新城疫病毒病毒粒子中的核糖核酸聚合酶:与水疱性口炎病毒聚合酶的比较。

Ribonucleic acid polymerase in virions of Newcastle disease virus: comparison with the vesicular stomatitis virus polymerase.

作者信息

Huang A S, Baltimore D, Bratt M A

出版信息

J Virol. 1971 Mar;7(3):389-94. doi: 10.1128/JVI.7.3.389-394.1971.

Abstract

The virions of Newcastle disease virus (NDV) contained an enzyme that catalyzed the incorporation of ribonucleotides into ribonucleic acid (RNA). Optimal conditions for this polymerase activity were identical to the conditions for the vesicular stomatitis virus (VSV) polymerase, and both enzymes were active for longer times at 32 C than at 37 C. However, the specific activity of the NDV polymerase was less than 3% that of the VSV polymerase. Product RNA species from the NDV and VSV polymerase reactions annealed specifically to the homologous virion RNA species. Transcriptive intermediates containing product RNA attached to the respective virion RNA could be identified in both systems.

摘要

新城疫病毒(NDV)的病毒粒子含有一种能催化核糖核苷酸掺入核糖核酸(RNA)的酶。这种聚合酶活性的最佳条件与水泡性口炎病毒(VSV)聚合酶的条件相同,并且两种酶在32℃下比在37℃下具有更长时间的活性。然而,NDV聚合酶的比活性不到VSV聚合酶的3%。NDV和VSV聚合酶反应产生的RNA产物能与同源病毒粒子RNA特异性退火。在两个系统中都能鉴定出含有附着在各自病毒粒子RNA上的产物RNA的转录中间体。

相似文献

4
Complete transcription by the transcriptase of vesicular stomatitis virus.
J Virol. 1971 Apr;7(4):486-90. doi: 10.1128/JVI.7.4.486-490.1971.
6
Ribonucleic acid synthesis of vesicular stomatitis virus, II. An RNA polymerase in the virion.
Proc Natl Acad Sci U S A. 1970 Jun;66(2):572-6. doi: 10.1073/pnas.66.2.572.
8
RNA-dependent RNA polymerase activity associated with virions and subviral particles of myxoviruses.
Proc Natl Acad Sci U S A. 1971 Apr;68(4):752-6. doi: 10.1073/pnas.68.4.752.
10
Ribonucleic acid transcriptases in Sendai Virions and infected cells.
J Virol. 1971 Aug;8(2):174-80. doi: 10.1128/JVI.8.2.174-180.1971.

引用本文的文献

1
Noncytopathic mutants of Newcastle disease virus are defective in virus-specific RNA synthesis.
J Virol. 1981 Jan;37(1):317-27. doi: 10.1128/JVI.37.1.317-327.1981.
3
Coding assignments of the five smaller mRNAs of Newcastle disease virus.
J Virol. 1982 Sep;43(3):1024-31. doi: 10.1128/JVI.43.3.1024-1031.1982.
4
Characterization of two RNA polymerase activities induced by mouse hepatitis virus.
J Virol. 1982 Jun;42(3):847-53. doi: 10.1128/JVI.42.3.847-853.1982.
5
RNA-dependent RNA polymerase activity in coronavirus- infected cells.
J Virol. 1982 Apr;42(1):153-64. doi: 10.1128/JVI.42.1.153-164.1982.
6
Viruses with segmented ribonucleic acid genomes: multiplication of influenza versus reovirus.
Bacteriol Rev. 1971 Sep;35(3):250-66. doi: 10.1128/br.35.3.250-266.1971.
9
RNA polymerase in mumps virion.
J Virol. 1974 Jul;14(1):183-6. doi: 10.1128/JVI.14.1.183-186.1974.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75.
3
Newcastle disease virus RNA. I. Isolation and preliminary characterization of RNA from virus particles.
J Mol Biol. 1966 Jun;18(1):195-203. doi: 10.1016/s0022-2836(66)80085-2.
4
Isolation and properties of Newcastle disease virus nucleocapsid.
J Virol. 1968 Mar;2(3):248-55. doi: 10.1128/JVI.2.3.248-255.1968.
5
6
Isolation of the nucleic acid of Newcastle disease virus (NDV).
Proc Natl Acad Sci U S A. 1965 Sep;54(3):794-800. doi: 10.1073/pnas.54.3.794.
10
Complementary RNAs in paramyxovirions and paramyxovirus-infected cells.
Nature. 1970 Dec 19;228(5277):1196-7. doi: 10.1038/2281196a0.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验