Roy P, Bishop D H
J Virol. 1972 Jun;9(6):946-55. doi: 10.1128/JVI.9.6.946-955.1972.
The small defective T particle of vesicular stomatitis virus (VSV-111) has no detectable enzyme activity when assayed at 31 C, although qualitatively it possesses all the virion proteins found in complete VSV-1 virions. With VSV-1 transcription product ribonucleic acid (RNA), it is shown that the VSV-111 RNA is identical to part of the VSV-1 genome. Evidence is also presented to support the idea that in vitro VSV-1 transcription is sequential.
水泡性口炎病毒的小型缺陷T颗粒(VSV - 111)在31℃下检测时没有可检测到的酶活性,尽管从质量上看它拥有完整VSV - 1病毒体中发现的所有病毒粒子蛋白。对于VSV - 1转录产物核糖核酸(RNA),研究表明VSV - 111 RNA与VSV - 1基因组的一部分相同。同时也提供了证据来支持体外VSV - 1转录是按顺序进行的这一观点。