Bishop D H, Obijeski J F, Simpson R W
J Virol. 1971 Jul;8(1):74-80. doi: 10.1128/JVI.8.1.74-80.1971.
The properties of the ribonucleic acid (RNA) synthesized by the influenza (WSN) virion polymerase have been investigated. Most of the product RNA is synthesized in association with virion RNA species from which it can be released by heat treatment as single-stranded, ribonuclease-sensitive polynucleotides (average molecular weight, 2-hr sample, about 10(5) daltons). At least 95% of the product is complementary to the viral RNA species. On the basis of the molar ratio of the RNA species isolated from a (3)H-uridine-labeled virus preparation, it was calculated that the WSN genome consists of seven pieces of RNA with a sum molecular weight of about 5 x 10(6) daltons.
对流感（WSN）病毒粒子聚合酶合成的核糖核酸（RNA）的特性进行了研究。大部分产物RNA是与病毒粒子RNA种类相关联合成的，通过热处理可将其作为单链、对核糖核酸酶敏感的多核苷酸释放出来（平均分子量，2小时样本，约10⁵道尔顿）。至少95%的产物与病毒RNA种类互补。根据从³H-尿苷标记的病毒制剂中分离出的RNA种类的摩尔比计算得出，WSN基因组由七条RNA片段组成，总分子量约为5×10⁶道尔顿。
