Grodzicker T, Arditti R R, Eisen H
Proc Natl Acad Sci U S A. 1972 Feb;69(2):366-70. doi: 10.1073/pnas.69.2.366.
Lambdoid phages form clear plaques and show reduced ability to establish immunity in strains of Escherichia coli that lack adenylate cyclase or catabolite activator protein. The absence of the activator protein or cyclic AMP reduces the frequency of lysogenization, but does not prevent steady-state repressor synthesis of a lysogen. Lambda phage mutants able to form turbid plaques on strains that lack catabolite activator protein or adenylate cyclase have been isolated and analyzed.
λ噬菌体形成清亮噬菌斑,并且在缺乏腺苷酸环化酶或分解代谢物激活蛋白的大肠杆菌菌株中建立免疫的能力降低。激活蛋白或环磷酸腺苷的缺失会降低溶源化频率,但不会阻止溶源菌中阻遏物的稳态合成。已经分离并分析了能够在缺乏分解代谢物激活蛋白或腺苷酸环化酶的菌株上形成混浊噬菌斑的λ噬菌体突变体。