Blanck R R, Ream N, Conrad M
Am J Gastroenterol. 1979 Feb;71(2):164-7.
Hepatitis B surface antigen (HBsAg) and antibody (anti-HBsAg) were determined on 442 asymptomatic heroin users and 246 controls. Of the drug-taking group, 124 used heroin intravenously and 318 nonintravenously (smoking, sniffing). Twenty-three (5.2%) heroin users were HBsAg positive and 118 (26.7%) anti-HBsAg positive, compared to three (1.2%) HBsAg positive and 28 (11.4%) anti-HBsAg positive controls, both statistically significant. HBsAg was positive in eight (6.5%) intravenous heroin users and statistically identical to 15 (4.7%) HBsAg positive nonintravenous users. Positive anti-HBsAg in 55 (44.4%) intravenous heroin users compared to 63 (19.8%) nonintravenous users, however, is statistically significicant.
对442名无症状海洛因使用者和246名对照者进行了乙肝表面抗原(HBsAg)和抗体(抗-HBsAg)检测。在吸毒组中,124人静脉注射海洛因,318人非静脉注射(吸烟、嗅吸)。23名(5.2%)海洛因使用者HBsAg呈阳性,118名(26.7%)抗-HBsAg呈阳性,相比之下,3名(1.2%)对照者HBsAg呈阳性,28名(11.4%)对照者抗-HBsAg呈阳性,两者均具有统计学意义。8名(6.5%)静脉注射海洛因使用者HBsAg呈阳性,与15名(4.7%)非静脉注射海洛因使用者HBsAg呈阳性在统计学上无差异。然而,55名(44.4%)静脉注射海洛因使用者抗-HBsAg呈阳性,相比之下63名(19.8%)非静脉注射海洛因使用者抗-HBsAg呈阳性,具有统计学意义。