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小鼠白血病：血清干扰素产生受抑制。

Mouse leukemia: depression of serum interferon production.

作者信息

De Maeyer-Guignard J

出版信息

Science. 1972 Sep 1;177(4051):797-9. doi: 10.1126/science.177.4051.797.

DOI:10.1126/science.177.4051.797
PMID:4340758
Abstract

Production of circulating interferon is significantly impaired in AKR/J mice after development of lymphoblastic leukemia and in Balb/c mice with clinical signs of Friend erythroblastic leukemia. This alteration has been observed with three interferon inducers, each one known to elicit an interferon response in different cells.

摘要

在淋巴细胞白血病发生后，AKR/J小鼠以及出现弗氏成红细胞白血病临床症状的Balb/c小鼠中，循环干扰素的产生显著受损。使用三种干扰素诱导剂时均观察到了这种改变，已知每种诱导剂都会在不同细胞中引发干扰素反应。

相似文献

1
Mouse leukemia: depression of serum interferon production.小鼠白血病：血清干扰素产生受抑制。
Science. 1972 Sep 1;177(4051):797-9. doi: 10.1126/science.177.4051.797.
2
Therapeutic effects of a series of non-viral interferon inducers on a viral-induced leukemia.一系列非病毒干扰素诱导剂对病毒诱导的白血病的治疗作用。
Can J Microbiol. 1971 Oct;17(10):1259-65. doi: 10.1139/m71-202.
3
Interferon inducers: enhancement of viral oncogenesis in mice and rats.干扰素诱导剂：对小鼠和大鼠病毒致癌作用的增强
Proc Soc Exp Biol Med. 1972 Apr;139(4):1132-7. doi: 10.3181/00379727-139-36314.
4
Prostaglandin restoration of the interferon response of hyporeactive animals.
Science. 1978 Jul 28;201(4353):376-8. doi: 10.1126/science.208154.
5
Amelioration of friend virus leukemia by sequential administration of viral and nonviral interferon inducers.通过依次给予病毒和非病毒干扰素诱导剂改善Friend病毒白血病。
Proc Soc Exp Biol Med. 1971 Jul;137(3):981-7. doi: 10.3181/00379727-137-35710.
6
The role of interferon in the spontaneous regression of Friend virus induced leukemia.干扰素在弗瑞德病毒诱发白血病自然消退中的作用。
Proc Soc Exp Biol Med. 1975 Oct;150(1):11-13. doi: 10.3181/00379727-150-38963.
7
Murine leukemia: depressed response to interferon induction correlated with a serum hyporeactive factor.鼠白血病：对干扰素诱导的反应性降低与血清低反应性因子相关。
Infect Immun. 1976 Feb;13(2):392-8. doi: 10.1128/iai.13.2.392-398.1976.
8
Suppression of established Friend virus leukemia by statolon. VII. Relative roles of interferon and the immune response in development of FV-dormant infections.制瘤素对已确立的弗氏病毒白血病的抑制作用。VII. 干扰素和免疫反应在弗氏病毒潜伏感染发展中的相对作用。
Proc Soc Exp Biol Med. 1973 Jul;143(3):726-32. doi: 10.3181/00379727-143-37401.
9
Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins.与前列腺素联合给药的干扰素诱导剂的抗病毒及诱导干扰素特性
Antimicrob Agents Chemother. 1980 Mar;17(3):455-60. doi: 10.1128/AAC.17.3.455.
10
Interferon and host resistance to Rauscher virus-induced leukemia.干扰素与宿主对劳氏病毒诱导白血病的抵抗力
J Virol. 1969 Feb;3(2):99-105. doi: 10.1128/JVI.3.2.99-105.1969.

引用本文的文献

1
Is a compromised interferon response an etiologic factor in Reye's syndrome?干扰素反应受损是瑞氏综合征的病因之一吗？
Can Med Assoc J. 1982 Apr 1;126(7):798-802.
2
Interferons, a group of multiple lymphokines.干扰素，一组多种淋巴因子。
Springer Semin Immunopathol. 1984;7(4):347-74. doi: 10.1007/BF00201966.
3
Hyporeactivity due to infection: recognition of a transferable hyporeactive factor in the serum of encephalomyocarditis virus-infected mice.感染引起的反应性降低：在脑心肌炎病毒感染小鼠血清中识别一种可转移的低反应性因子。
Infect Immun. 1974 Dec;10(6):1337-42. doi: 10.1128/iai.10.6.1337-1342.1974.
4
Lead aggravates viral disease and represses the antiviral activity of interferon inducers.铅会加重病毒性疾病，并抑制干扰素诱导剂的抗病毒活性。
Environ Health Perspect. 1974 May;7:113-9. doi: 10.1289/ehp.747113.
5
Mycoplasma-mediated hyporeactivity to various interferon inducers.支原体介导的对各种干扰素诱导剂的反应性降低。
Infect Immun. 1975 Dec;12(6):1349-54. doi: 10.1128/iai.12.6.1349-1354.1975.
6
Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Identification of the anti-viral activity as interferon and characterization of the human effector lymphocyte subpopulation.通过将淋巴细胞与肿瘤衍生细胞或病毒转化细胞共培养诱导产生的抗病毒活性。将抗病毒活性鉴定为干扰素，并对人类效应淋巴细胞亚群进行表征。
J Exp Med. 1978 May 1;147(5):1299-1313. doi: 10.1084/jem.147.5.1299.
7
Hyporeactivity to interferon induction: characterization of a hyporeactive factor in the serum of encephalomyocarditis virus-infected mice.对干扰素诱导反应低下：脑心肌炎病毒感染小鼠血清中反应低下因子的特性研究
Infect Immun. 1975 Feb;11(2):294-302. doi: 10.1128/iai.11.2.294-302.1975.
8
Murine leukemia: depressed response to interferon induction correlated with a serum hyporeactive factor.鼠白血病：对干扰素诱导的反应性降低与血清低反应性因子相关。
Infect Immun. 1976 Feb;13(2):392-8. doi: 10.1128/iai.13.2.392-398.1976.