小鼠白血病：血清干扰素产生受抑制。
Mouse leukemia: depression of serum interferon production.
作者信息
De Maeyer-Guignard J
出版信息
Science. 1972 Sep 1;177(4051):797-9. doi: 10.1126/science.177.4051.797.
PMID:4340758
Abstract
Production of circulating interferon is significantly impaired in AKR/J mice after development of lymphoblastic leukemia and in Balb/c mice with clinical signs of Friend erythroblastic leukemia. This alteration has been observed with three interferon inducers, each one known to elicit an interferon response in different cells.
摘要
在淋巴细胞白血病发生后，AKR/J小鼠以及出现弗氏成红细胞白血病临床症状的Balb/c小鼠中，循环干扰素的产生显著受损。使用三种干扰素诱导剂时均观察到了这种改变，已知每种诱导剂都会在不同细胞中引发干扰素反应。
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