蠕虫感染对大鼠反应素（IgE）抗体的增强作用。不同反应素的同时增强。
Potentiation of rat reaginic (IgE) antibody by helminth infection. Simultaneous potentiation of separate reagins.
作者信息
Jarrett E E, Stewart D C
出版信息
Immunology. 1972 Nov;23(5):749-55.
Further evidence has been produced that rat reaginic antibody responses which have been programmed by the injection of antigen with can be greatly potentiated by a subsequent infection with the helminth parasite . Potentiated responses to keyhole limpet haemocyanin and house dust extract have been demonstrated. It is shown that the timing of the parasitic infection must take into account the kinetics of the reagin response to the particular antigen under test. Simultaneous potentiation of two reagin responses could be demonstrated; occasionally selective potentiation of one reagin response was found to occur. The possible relevance of these mechanisms for the development of clinically manifest immediate hypersensitivity is discussed.
进一步的证据表明，通过注射抗原预先设定的大鼠反应素抗体反应，可因随后感染蠕虫寄生虫而大大增强。已证实对钥孔戚血蓝蛋白和屋尘提取物的反应增强。结果表明，寄生虫感染的时机必须考虑到对特定测试抗原的反应素反应动力学。可以证明两种反应素反应同时增强；偶尔也会发现一种反应素反应的选择性增强。本文讨论了这些机制与临床明显的速发型超敏反应发展的可能相关性。
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