慢性γ-丁内酯（GBL）治疗：一种多巴胺活性低下的潜在模型。 - Suppr

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Chronic gamma-butyrolactone (GBL) treatment: a potential model of dopamine hypoactivity.

作者信息

Nowycky M C, Roth R H

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1979 Nov;309(3):247-54. doi: 10.1007/BF00504757.

DOI:10.1007/BF00504757

PMID:43476

Abstract

摘要

相似文献

Chronic gamma-butyrolactone (GBL) treatment: a potential model of dopamine hypoactivity.慢性γ-丁内酯（GBL）治疗：一种多巴胺活性低下的潜在模型。

Naunyn Schmiedebergs Arch Pharmacol. 1979 Nov;309(3):247-54. doi: 10.1007/BF00504757.

An investigation of the relationship between the dopaminergic and electroencephalographic effects of gamma-butyrolactone.γ-丁内酯的多巴胺能效应与脑电图效应之间关系的研究。

Neuropharmacology. 1982 Jun;21(6):539-43. doi: 10.1016/0028-3908(82)90044-2.

Dopaminergic neurons: reversal of effects elicited by gamma-butyrolactone by stimulation of the nigro-neostriatal pathway.多巴胺能神经元：通过刺激黑质-新纹状体通路逆转γ-丁内酯引发的效应。

Naunyn Schmiedebergs Arch Pharmacol. 1976 Oct;295(1):15-20. doi: 10.1007/BF00509766.

Tolerance to the effects of baclofen and gamma-butyrolactone on locomotor activity and dopaminergic neurons in the mouse.小鼠对巴氯芬和γ-丁内酯对运动活动及多巴胺能神经元影响的耐受性。

J Pharmacol Exp Ther. 1978 Dec;207(3):859-69.

Evidence for down-regulation of GABA receptors following long-term gamma-butyrolactone.长期使用γ-丁内酯后γ-氨基丁酸受体下调的证据。

Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov;328(1):62-8. doi: 10.1007/BF00496108.

Presynaptic inhibition of nigrostriatal dopamine release in the mouse: lack of cross tolerance between apomorphine, GBL and CGS 10746B.小鼠黑质纹状体多巴胺释放的突触前抑制：阿扑吗啡、GBL和CGS 10746B之间缺乏交叉耐受性。

Life Sci. 1988;42(16):1503-6. doi: 10.1016/0024-3205(88)90006-9.

Differential actions of dopamine agonists and antagonists on the gamma-butyrolactone-induced in mouse brain dopamine.多巴胺激动剂和拮抗剂对γ-丁内酯诱导的小鼠脑内多巴胺的不同作用。

Psychopharmacology (Berl). 1976 Nov 24;50(3):225-9. doi: 10.1007/BF00426836.

Gamma-butyrolactone sleep: A 24-hour rhythm paralleling normal sleep in the rat and CNS amine changes.γ-丁内酯睡眠：与大鼠正常睡眠及中枢神经系统胺类变化平行的24小时节律。

Pharmacol Biochem Behav. 1975 Sep-Oct;3(5):761-4. doi: 10.1016/0091-3057(75)90103-3.

Altered activation of tyrosine hydroxylation by gamma-butyrolactone following chronic ethanol treatment.慢性乙醇处理后γ-丁内酯对酪氨酸羟化作用激活的改变。

Drug Alcohol Depend. 1979 May-Jul;4(3-4):261-3. doi: 10.1016/0376-8716(79)90008-5.

gamma-Butyrolactone effects on behavior induced by dopamine agonists.γ-丁内酯对多巴胺激动剂诱导行为的影响。

Biol Psychiatry. 1983 Sep;18(9):1023-32.

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Effect of chronic γ-hydroxybutyrate (GHB) administration on GHB toxicokinetics and GHB-induced respiratory depression.长期给予γ-羟基丁酸（GHB）对GHB毒代动力学及GHB所致呼吸抑制的影响。

Am J Drug Alcohol Abuse. 2017 Nov;43(6):686-693. doi: 10.1080/00952990.2017.1339055. Epub 2017 Jun 29.

Decreased 3H-L-quinuclidinyl benzilate binding and muscarine receptor subsensitivity after chronic gamma-butyrolactone treatment.慢性γ-丁内酯治疗后3H-东莨菪碱结合减少及毒蕈碱受体亚敏感性降低。

Naunyn Schmiedebergs Arch Pharmacol. 1981 Dec;318(1):14-8. doi: 10.1007/BF00503306.

Evidence for down-regulation of GABA receptors following long-term gamma-butyrolactone.长期使用γ-丁内酯后γ-氨基丁酸受体下调的证据。

Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov;328(1):62-8. doi: 10.1007/BF00496108.

本文引用的文献

THE ACTION OF SODIUM 4-HYDROXYBUTYRATE ON SPINAL REFLEXES.4-羟基丁酸钠对脊髓反射的作用

Br J Pharmacol Chemother. 1964 Apr;22(2):318-28. doi: 10.1111/j.1476-5381.1964.tb02036.x.

The effect of tropolone on the formation of 3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid in the brain of the mouse.托酚酮对小鼠脑中3,4-二羟基苯乙酸和4-羟基-3-甲氧基苯乙酸形成的影响。

Br J Pharmacol. 1969 May;36(1):107-15. doi: 10.1111/j.1476-5381.1969.tb08308.x.

Mechanism of the gamma-hydroxybutyrate-induced increase in brain dopamine and its relationship to "sleep".γ-羟基丁酸诱导脑内多巴胺增加的机制及其与“睡眠”的关系。

Biochem Pharmacol. 1970 Dec;19(12):3001-12. doi: 10.1016/0006-2952(70)90086-9.

Gamma-hydroxybutyrate-induced increase in brain dopamine: localization by fluorescence microscopy.γ-羟基丁酸引起的脑内多巴胺增加：通过荧光显微镜进行定位

J Pharmacol Exp Ther. 1970 Oct;175(1):131-8.

Stimulation of brain dopamine synthesis by gamma-hydroxybutyrate.γ-羟基丁酸对脑多巴胺合成的刺激作用。

J Neurochem. 1971 Oct;18(10):1831-6. doi: 10.1111/j.1471-4159.1971.tb09588.x.

The fluorometric assay of catecholamines and related compounds: improvements and extensions to the hydroxyindole technique.儿茶酚胺及相关化合物的荧光测定法：对羟基吲哚技术的改进与扩展

Anal Biochem. 1968 Feb;22(2):269-79. doi: 10.1016/0003-2697(68)90316-3.

Dopaminergic neurons: similar biochemical and histochemical effects of gamma-hydroxybutyrate and acute lesions of the nigro-neostriatal pathway.多巴胺能神经元：γ-羟基丁酸与黑质-新纹状体通路急性损伤的相似生化和组织化学效应。

J Pharmacol Exp Ther. 1973 Sep;186(3):630-9.

Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum.γ-羟基丁酸对大鼠纹状体中多巴胺及多巴胺代谢产物的影响。

Biochem Pharmacol. 1972 Aug 1;21(15):2111-21. doi: 10.1016/0006-2952(72)90164-5.

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.多巴胺能神经元：抗精神病药物和苯丙胺对单细胞活性的影响。

J Pharmacol Exp Ther. 1973 Jun;185(3):560-71.

Pharmacologically induced behavioural supersensitivity to apomorphine.药物诱导的对阿扑吗啡的行为超敏反应。

Nat New Biol. 1973 Oct 31;245(148):262-3. doi: 10.1038/newbio245262a0.

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