Fisher M L, Parisi A F, Plotnick G D, DeFelice C E, Carliner N H, Fortuin N J
Arch Intern Med. 1979 Apr;139(4):402-6.
Mitral valve area (MVA) determined at cardiac catheterization was compared with M mode echocardiographic measurements in 44 patients with mitral stenosis and no substantial mitral regurgitation. Despite statistically significant correlations, measurements of anterior leaflet motion, including rate of diastolic closure (EF slope) were not useful in predicting severity of stenosis. In contrast, maximal diastolic separation of anterior and posterior leaflets (SEP) was more closely correlated with MVA and appears to have some predictive value. Narrow separation was associated with severe mitral stenosis. Wide separation was associated with relatively mild stenosis. Intermediate values in 16 of 44 patients (36%) were not of predictive value. Recognizing this limitation, measurement of maximal diastolic mitral leaflet separation from M mode echocardiograms is proposed as a simple and useful method for assessing severity of mitral stenosis.
在44例二尖瓣狭窄且无明显二尖瓣反流的患者中，对心导管检查测定的二尖瓣面积（MVA）与M型超声心动图测量结果进行了比较。尽管存在统计学上的显著相关性，但前叶运动的测量值，包括舒张期关闭速率（EF斜率），在预测狭窄严重程度方面并无用处。相比之下，前后叶最大舒张期分离度（SEP）与MVA的相关性更强，似乎具有一定的预测价值。分离度窄与严重二尖瓣狭窄相关。分离度宽与相对较轻的狭窄相关。44例患者中有16例（36%）的中间值无预测价值。认识到这一局限性后，建议通过M型超声心动图测量二尖瓣叶最大舒张期分离度，作为评估二尖瓣狭窄严重程度的一种简单且有用的方法。
