一种基于涂有醋酸纤维素超薄膜的活性炭颗粒的血液灌流柱。

A hemoperfusion column based on activated carbon granules coated with an ultrathin membrane of cellulose acetate.

作者信息

Tijssen J, Bantjes A, van Doorn A W, Feijen J, van Dijk B, Vonk C R, Dijkhuis I C

出版信息

Artif Organs. 1979 Feb;3(1):11-4. doi: 10.1111/j.1525-1594.1979.tb03797.x.

DOI:10.1111/j.1525-1594.1979.tb03797.x

Abstract

A hemoperfusion system has been developed which makes use of activated carbon encapsulated with cellulose acetate. Studies have revealed that there are no stagnant flow regions in the column, there is minimal particle release and the coating is 30 A thick. The relationships between pore size, pore volume and surface area have been examined. Twenty-five patients in grade IV coma have been treated with the column for treatment of drug overdose or agricultural chemical poisoning; the clinical course of one meprobamate-poisoned patient is described in detail.

摘要

一种利用醋酸纤维素包裹活性炭的血液灌流系统已被研发出来。研究表明，该柱体中不存在滞流区域，颗粒释放极少，且涂层厚度为30埃。已对孔径、孔体积和表面积之间的关系进行了研究。25名处于IV级昏迷的患者已使用该柱体治疗药物过量或农药中毒；详细描述了一名眠尔通中毒患者的临床病程。