破伤风毒素的作用机制：对突触过程的影响以及神经组织结合毒素的一些特殊特征。 - Suppr

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The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.

作者信息

Kryzhanovsky G N

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):247-70. doi: 10.1007/BF00499880.

DOI:10.1007/BF00499880

PMID:4351283

Abstract

摘要

相似文献

The mechanism of action of tetanus toxin: effect on synaptic processes and some particular features of toxin binding by the nervous tissue.破伤风毒素的作用机制：对突触过程的影响以及神经组织结合毒素的一些特殊特征。

Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):247-70. doi: 10.1007/BF00499880.

Distribution of 125 I-tetanus toxin and 125 I-toxoid in rats with generalized tetanus, as influenced by antitoxin.抗毒素对全身性破伤风大鼠体内¹²⁵I-破伤风毒素和¹²⁵I-类毒素分布的影响

Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):327-40. doi: 10.1007/BF00499887.

Distribution of 125 I-tetanus toxin and 125 I-toxoid in rats with local tetanus, as influenced by antitoxin.抗毒素对局部破伤风大鼠体内125I-破伤风毒素和125I-类毒素分布的影响

Naunyn Schmiedebergs Arch Pharmacol. 1972;272(1):75-88. doi: 10.1007/BF00498795.

The effects of tetanus toxin on the motor end-plates of the mouse. An electron microscopic study.破伤风毒素对小鼠运动终板的影响。一项电子显微镜研究。

J Neurol Sci. 1973 Jun;19(2):153-67. doi: 10.1016/0022-510x(73)90159-7.

Botulinum toxin and tetanus toxin recognize similar membrane determinants.肉毒杆菌毒素和破伤风毒素识别相似的膜决定簇。

Brain Res. 1984 Jul 2;305(1):177-80. doi: 10.1016/0006-8993(84)91136-3.

Pharmacokinetic and histoautoradiographic evidence for the intraaxonal movement of toxin in the pathogenesis of tetanus.破伤风发病机制中轴突内毒素移动的药代动力学和组织放射自显影证据。

Toxicon. 1978;16(6):611-23. doi: 10.1016/0041-0101(78)90189-7.

Pathogenesis of local tetanus in rats: neural ascent of tetanus toxin.大鼠局部破伤风的发病机制：破伤风毒素的神经上行

Naunyn Schmiedebergs Arch Pharmacol. 1974;281(4):391-401. doi: 10.1007/BF00499434.

Lectins from Triticum vulgaris and Limax flavus are universal antagonists of botulinum neurotoxin and tetanus toxin.来自普通小麦和黄蛞蝓的凝集素是肉毒杆菌神经毒素和破伤风毒素的通用拮抗剂。

J Pharmacol Exp Ther. 1991 Sep;258(3):830-6.

Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin.破伤风毒素在体外像肉毒杆菌A毒素一样阻断神经肌肉传导。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Feb;311(1):33-40. doi: 10.1007/BF00500299.

Interaction of labelled tetanus toxin with substructures of rat spinal cord in vivo.体内标记破伤风毒素与大鼠脊髓亚结构的相互作用

Naunyn Schmiedebergs Arch Pharmacol. 1973;276(3-4):361-73. doi: 10.1007/BF00499889.

引用本文的文献

Blockade by tetanus and botulinum A toxin of postganglionic cholinergic nerve endings in the myenteric plexus.破伤风毒素和肉毒杆菌A毒素对肌间神经丛中节后胆碱能神经末梢的阻断作用。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Jul;312(3):255-63. doi: 10.1007/BF00499155.

Inhibition of synaptosomal choline uptake by tetanus and botulinum A toxin. Partial dissociation of fixation and effect of tetanus toxin.破伤风毒素和肉毒杆菌A毒素对突触体胆碱摄取的抑制作用。破伤风毒素固定作用与效应的部分解离

Naunyn Schmiedebergs Arch Pharmacol. 1981 Apr;316(2):135-42. doi: 10.1007/BF00505307.

Efficacy of intravenous immunoglobulin preparations against viral and bacterial infections in mouse protection tests.静脉注射免疫球蛋白制剂在小鼠保护试验中对抗病毒和细菌感染的疗效。

Infection. 1983 Jul-Aug;11(4):227-31. doi: 10.1007/BF01641203.

Cephalic tetanus studied with single fibre EMG.用单纤维肌电图研究头面部破伤风。

J Neurol Neurosurg Psychiatry. 1983 Sep;46(9):862-6. doi: 10.1136/jnnp.46.9.862.

Effect of tetanus toxin on the excitatory and the inhibitory post-synaptic potentials in the cat motoneurone.破伤风毒素对猫运动神经元兴奋性和抑制性突触后电位的影响。

J Physiol. 1983 Feb;335:319-33. doi: 10.1113/jphysiol.1983.sp014536.

Clostridium botulinum neurotoxin.肉毒梭菌神经毒素

Microbiol Rev. 1980 Sep;44(3):419-48. doi: 10.1128/mr.44.3.419-448.1980.

Tetanus toxin blocks the neuromuscular transmission in vitro like botulinum A toxin.破伤风毒素在体外像肉毒杆菌A毒素一样阻断神经肌肉传导。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Feb;311(1):33-40. doi: 10.1007/BF00500299.

Transmitter release in tetanus and botulinum A toxin-poisoned mammalian motor endplates and its dependence on nerve stimulation and temperature.破伤风毒素和肉毒杆菌A毒素中毒的哺乳动物运动终板中的递质释放及其对神经刺激和温度的依赖性。

Pflugers Arch. 1983 Nov;399(3):228-34. doi: 10.1007/BF00656720.

At least three sequential steps are involved in the tetanus toxin-induced block of neuromuscular transmission.

Naunyn Schmiedebergs Arch Pharmacol. 1981;317(4):326-30. doi: 10.1007/BF00501314.

Discrimination between binding to CNS, toxicity and immunreactivity of derivatives of tetanus toxin.破伤风毒素衍生物与中枢神经系统结合、毒性及免疫反应性之间的鉴别

Med Microbiol Immunol. 1973 Sep 26;159(1):89-100. doi: 10.1007/BF02122653.

本文引用的文献

The immunochemistry of toxins and toxoids; the preparation and immunologic evaluation of purified tetanol toxoid.毒素与类毒素的免疫化学；纯化破伤风类毒素的制备及免疫学评估。

J Immunol. 1946 Nov;54(3):213-24.

The movements of toxin in the nervous system in experimental tetanus in rabbits.毒素在兔实验性破伤风神经系统中的运动

Br J Exp Pathol. 1951 Jun;32(3):169-82.

Separation of univalent fragments from the bivalent rabbit antibody molecule by reduction of disulfide bonds.通过二硫键还原从二价兔抗体分子中分离单价片段。

Arch Biochem Biophys. 1960 Aug;89:230-44. doi: 10.1016/0003-9861(60)90049-7.

FIXATION OF TETANUS TOXIN BY SUBCELLULAR FRACTIONS OF BRAIN.破伤风毒素与脑亚细胞组分的结合

J Neurochem. 1965 Feb;12:77-9. doi: 10.1111/j.1471-4159.1965.tb11941.x.

[THE FATE OF LABELED TETANUS TOXIN IN THE ANIMAL ORGANISM].[标记破伤风毒素在动物机体内的命运]

Zh Mikrobiol Epidemiol Immunobiol. 1964 Sep;41:123-9.

OBSERVATIONS ON THE PASSAGE OF THE FLUORESCEIN LABELED SERUM PROTEINS (FLSP) FROM THE CEREBROSPINAL FLUID.关于荧光素标记血清蛋白（FLSP）从脑脊液中的通过情况的观察

J Neuropathol Exp Neurol. 1964 Jan;23:18-35. doi: 10.1097/00005072-196401000-00002.

Electron microscopy of presynaptic organelles of the spinal cord.脊髓突触前细胞器的电子显微镜检查。

J Anat. 1963 Jan;97(Pt 1):101-6.

The fixation of tetanus toxin by ganglioside.破伤风毒素与神经节苷脂的结合

J Gen Microbiol. 1961 Jan;24:107-19. doi: 10.1099/00221287-24-1-107.

Penetration of radioactive bovine albumin from cerebrospinal fluid into brain tissue.放射性牛血清白蛋白从脑脊液进入脑组织的渗透情况。

Neurology. 1960 Sep;10:814-22. doi: 10.1212/wnl.10.9.814.

The thiobarbituric acid assay of sialic acids.唾液酸的硫代巴比妥酸测定法。

J Biol Chem. 1959 Aug;234(8):1971-5.

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