Lamm H, Alm W
Arch Otorhinolaryngol. 1979;222(2):145-51. doi: 10.1007/BF00469754.
Guinea pigs were treated with 3 bar oxygen pressure in a hyperbaric chamber and CMs and APs were simultaneously registrated. The results depended on the kind of the usual anesthesy. If nembutal i.p. was used, the CMs and APs had been increased significant shortly after oxygen pressure reached 3 bar (CMs increased more than APs). If urethane i.p. was used, the CMs and APs increases not so significantly. These results are traced back to the different effect of the both anesthetic drugs on the blood flow in the brain. Oxygen toxicity in the inner ear was observed after OHP of 3 bar more than 30 min but only by APs. The CMs didn't show any signs of oxygen toxicity under the same conditions during 60 min and more.
将豚鼠置于高压氧舱中，用3巴的氧压进行处理，并同时记录复合肌肉动作电位（CMs）和动作电位（APs）。结果取决于所用常规麻醉的类型。如果腹腔注射戊巴比妥，在氧压达到3巴后不久，CMs和APs显著增加（CMs的增加幅度大于APs）。如果腹腔注射乌拉坦，CMs和APs的增加则不那么显著。这些结果可归因于两种麻醉药物对脑血流的不同影响。在3巴的氧压下超过30分钟后，在内耳观察到氧中毒，但仅通过APs表现出来。在相同条件下60分钟及更长时间内，CMs未显示出任何氧中毒迹象。
