人女性尿液中雌激素葡糖醛酸苷的直接放射免疫测定法。
The direct radioimmunoassay of oestrogen glucuronides in human female urine.
作者信息
Baker T S, Jennison K M, Kellie A E
出版信息
Biochem J. 1979 Feb 1;177(2):729-38. doi: 10.1042/bj1770729.
Abstract
Radioimmunoassays for five oestrogen metabolites in urine are described; they are oestrone 3-glucuronide, oestradiol 3-glucuronide, oestradiol 17 beta-glucuronide, oestriol 3-glucuronide and oestriol 16 alpha-glucuronide. These assays have proved accurate and reliable and can be performed rapidly; they have been carried out directly in diluted menstrual cycle urine and pregnancy urine. No sample pretreatment was required. Preliminary results suggest that clinically useful information can be obtained by performing these assays on random urine specimens.
摘要
本文描述了尿液中五种雌激素代谢物的放射免疫测定法；它们分别是雌酮3-葡萄糖醛酸苷、雌二醇3-葡萄糖醛酸苷、雌二醇17β-葡萄糖醛酸苷、雌三醇3-葡萄糖醛酸苷和雌三醇16α-葡萄糖醛酸苷。这些测定法已被证明准确可靠，且能快速进行；它们可直接在稀释的月经周期尿液和妊娠尿液中进行。无需对样品进行预处理。初步结果表明，通过对随机尿液标本进行这些测定可获得临床有用信息。
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