从急性结膜炎病例中分离肠道病毒。
The isolation of enteroviruses from cases of acute conjunctivitis.
作者信息
Higgins P G, Scott R J
出版信息
J Clin Pathol. 1973 Sep;26(9):706-11. doi: 10.1136/jcp.26.9.706.
Abstract
In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.
摘要
在两次急性肠道病毒结膜炎疫情中，只有通过使用人胚胎器官培养才能确诊。在一个病例中，纤毛呼吸道上皮细胞培养物对该病毒敏感，但类似的培养未能支持从第二次疫情中分离出的病毒生长，该病毒是在结膜器官培养中分离出来的。与第三次疫情相关的病毒此前已通过在人胚肾细胞中培养从原始材料中分离出来，但在标本稀释后，需要在器官培养中传代才能检测到该病毒。
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本文引用的文献
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Further observations on the use of organ cultures in the study of acute respiratory-tract infections.关于器官培养在急性呼吸道感染研究中的应用的进一步观察。
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An epidemic of picornavirus conjunctivitis in Singapore.新加坡的肠道病毒结膜炎疫情。
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Growth of viruses in organ cultures of intestine.病毒在肠道器官培养物中的生长。
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The isolation of viruses from acute respiratory infections. V. The use of organ cultures of human embryonic nasal and tracheal ciliated epithelium.从急性呼吸道感染中分离病毒。五、人胚鼻和气管纤毛上皮器官培养物的应用。
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Cultivation of viruses from a high proportion of patients with colds.从很大比例的感冒患者身上培养出病毒。
Lancet. 1966 Jan 8;1(7428):76-7. doi: 10.1016/s0140-6736(66)92364-6.
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Pandemic of new type of conjunctivitis.
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