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补体对兔抗体中和小鼠巨细胞病毒的影响。

Influence of complement on the neutralization of murine cytomegalovirus by rabbit antibody.

作者信息

Kim K S, Carp R I

出版信息

J Virol. 1973 Dec;12(6):1620-1. doi: 10.1128/JVI.12.6.1620-1621.1973.

Abstract

Antiserum against murine cytomegalovirus produced in the rabbit contained complement (C')-requiring neutralizing (CRN) antibody. The proportion of CRN was extremely high (up to 98%) during the early portion of an immunization procedure, whereas the antisera produced late had a much lower proportion that required C'. The antiserum produced was specific for MCMV with or without C'.

摘要

在兔体内产生的抗鼠巨细胞病毒抗血清含有需要补体(C')的中和(CRN)抗体。在免疫程序早期,CRN的比例极高(高达98%),而后期产生的抗血清中需要C'的比例则低得多。所产生的抗血清对有或没有C'的鼠巨细胞病毒均具有特异性。

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