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人红细胞膜中环磷酸腺苷依赖性蛋白激酶定位的研究。

Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes.

作者信息

Rubin C S, Rosenfeld R D, Rosen O M

出版信息

Proc Natl Acad Sci U S A. 1973 Dec;70(12):3735-8. doi: 10.1073/pnas.70.12.3735.

Abstract

The topographic location of cyclic AMP-dependent protein kinase has been studied in preparations of permeable and sealed membranes derived from human erythrocytes. Both the catalytic and cyclic AMP-binding components of protein kinase are localized on the inner, cytoplasmic, surface of the plasma membrane.

摘要

已在源自人红细胞的可渗透和密封膜制剂中研究了环磷酸腺苷依赖性蛋白激酶的拓扑定位。蛋白激酶的催化成分和环磷酸腺苷结合成分均定位于质膜的内侧、细胞质表面。

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