Thomas D J, Kendall M J, Whitfield A G
Br Med J. 1974 Jan 26;1(5899):148-50. doi: 10.1136/bmj.1.5899.148.
In a review of 45 patients with ankylosing spondylitis 10 had neurological symptoms and signs and three of them had two separate neuropathological disorders. The neurological profiles fell into five main categories-multiple sclerosis, the cauda equina syndrome, focal epilepsy, vertebrobasilar insufficiency, and peripheral nerve lesions. An association between ankylosing spondylitis and multiple sclerosis is suggested, possibly due to an immunological defect or to one being a complication of the other.
在一项对45例强直性脊柱炎患者的回顾性研究中,10例有神经症状和体征,其中3例有两种不同的神经病理学疾病。神经学特征分为五大类——多发性硬化症、马尾综合征、局灶性癫痫、椎基底动脉供血不足和周围神经病变。提示强直性脊柱炎与多发性硬化症之间存在关联,可能是由于免疫缺陷或两者互为并发症。