van Someren H, Westerveld A, Hagemeijer A, Mees J R, Meera Khan P, Zaalberg O B
Proc Natl Acad Sci U S A. 1974 Mar;71(3):962-5. doi: 10.1073/pnas.71.3.962.
In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.
在人-中国仓鼠体细胞杂种中,研究了27种人类酶标记基因座以及包括HL-A组织相容性抗原在内的物种特异性表面抗原的分离情况。结果显示,磷酸葡萄糖变位酶3、胞质苹果酸酶、四聚体吲哚酚氧化酶和HL-A的人类基因座存在同线性。此外,有证据表明人类物种特异性抗原的基因座分布在几条染色体上。