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[仓鼠×绵羊杂种中的绵羊组织相容性复合体OLA和酶标记物。I. PGM3-ME1与OLA之间的不同源染色体。(作者译)]

[Ovine histocompatibility complex OLA and enzymatic markers in hamster X sheep hybrids. I. Asynteny between PGM3-ME1 and OLA. (author's transl)].

作者信息

Millot P, Saidi-Mehtar N, Hors-Cayla M C

出版信息

Ann Genet. 1981;24(2):82-8.

PMID:6460463
Abstract

Eighteen independent hamster X sheep fibroblast hybrids have been obtained. OLA typing of parental cells has shown that ovine fibroblasts carry the OLA A1, A8, B7, and B9 specificities. Analysis of the segregation of the OLA genes compared with the segregation of the 16 enzymatic markers studied previously indicated that, in contrast to the situation and man and certain other mammals, the genes of the histocompatibility complex of ovines (OLA) and those coding for the enzymes PGM3 and and ME1 are asyntenic. No synteny between OLA and any other enzymatic marker studied has been established.

摘要

已获得18个独立的仓鼠X绵羊成纤维细胞杂种。对亲代细胞进行的OLA分型显示,绵羊成纤维细胞携带OLA A1、A8、B7和B9特异性。将OLA基因的分离情况与之前研究的16种酶标记的分离情况进行比较分析表明,与人类和某些其他哺乳动物的情况不同,绵羊组织相容性复合体(OLA)的基因与编码酶PGM3和ME1的基因是非同线的。尚未确定OLA与所研究的任何其他酶标记之间存在同线性关系。

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