一个有霍奇金淋巴瘤聚集病例的城镇居民的淋巴细胞反应异常。
Abnormal lymphocyte responses in residents of a town with a cluster of Hodgkin's disease.
作者信息
Plouffe J F, Silva J, Schwartz R S, Callen J P, Kane P, Murphy L A, Goldstein I J, Fekety R
出版信息
Clin Exp Immunol. 1979 Feb;35(2):163-70.
A time-space aggregate of Hodgkin's disease was observed in a small town. A large elevator for the storage of navy beans was located in the residential area of the town. Lymphocytes of town residents compared to those of non-residents showed increased levels of transformations when challenged with extracts of navy beans. A phytohaemagglutinin from navy beans with the ability to stimulate lymphocytes was isolated and characterized. A hypothesis concerning a connection between this cluster of Hodgkin's disease and the abnormal lymphocyte responses to navy-bean phytohaemagglutinin is discussed.
在一个小镇上观察到了霍奇金病的时空聚集现象。小镇的居民区有一个用于储存海军豆的大型升降机。与非居民相比，城镇居民的淋巴细胞在用海军豆提取物刺激时，其转化水平有所提高。一种具有刺激淋巴细胞能力的来自海军豆的植物血凝素被分离并进行了表征。本文讨论了关于这一霍奇金病聚集现象与淋巴细胞对海军豆植物血凝素异常反应之间联系的假说。
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