Higgins P B
J Hyg (Lond). 1974 Jun;72(3):425-32. doi: 10.1017/s0022172400023664.
Influenza-like illness, cold and sore throat was the diagnosis given in over 80% of 5177 acute respiratory illnesses in patients swabbed over a 10-year-period. A pathogenic organism was isolated twice as frequently from patients with a sore throat or an influenza-like illness as from those diagnosed as suffering from croup or laryngitis and bronchitis. A laboratory diagnosis was commoner in school children than in older or younger persons.Most of the organisms isolated were found in association with all types of acute respiratory illness but, with increasing age of the patient, one particular agent or group of agents was more likely to be of aetiological significance.
在10年期间对5177例急性呼吸道疾病患者进行拭子采样,其中超过80%的诊断为流感样疾病、感冒和喉咙痛。从喉咙痛或流感样疾病患者中分离出致病生物的频率是诊断为患哮吼、喉炎和支气管炎患者的两倍。实验室诊断在学龄儿童中比在老年人或年轻人中更常见。分离出的大多数生物与所有类型的急性呼吸道疾病有关,但随着患者年龄的增加,一种特定的病原体或一组病原体更有可能具有病因学意义。