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淋病感染的血清学诊断

Serologic diagnosis of gonococcal infection.

作者信息

Gaafar H A

出版信息

Arch Androl. 1979 Dec;3(4):337-41. doi: 10.3109/01485017908988425.

DOI:10.3109/01485017908988425
PMID:43712
Abstract

Infection with N. gonorrhoeae stimulates the production of antibodies to many common, species-specific, and type-specific antigens. The L-antigen is an envelop antigen and antibodies to it could be demonstrated by various methods in more than 90% of the patients after the first 10 days of infection. Serologic tests are not yet available in the United States. If and when they become available, they may be recommended for: (1) Screening asymptomatic men and women, (2) Use as an adjunct diagnostic tool in cases of prostatitis, arthritis, disseminated gonococcal infection, and pelvic inflammatory disease, (3) Use (alone or in conjunction with culture) when specimens must be mailed to a central laboratory, when mailing conditions do not allow for incubation within 24-48 hr, or when proper media and qualified bacteriologists are not available.

摘要

感染淋病奈瑟菌会刺激机体产生针对许多常见、种特异性和型特异性抗原的抗体。L抗原是一种包膜抗原,感染10天后,超过90%的患者可通过多种方法检测到针对它的抗体。美国尚无血清学检测方法。如果且当有可用的血清学检测方法时,可能会推荐用于:(1)筛查无症状的男性和女性;(2)作为前列腺炎、关节炎、播散性淋球菌感染和盆腔炎病例的辅助诊断工具;(3)当标本必须邮寄到中央实验室、邮寄条件不允许在24 - 48小时内进行培养或没有合适的培养基和合格的细菌学家时使用(单独使用或与培养结合使用)。

相似文献

1
Serologic diagnosis of gonococcal infection.淋病感染的血清学诊断
Arch Androl. 1979 Dec;3(4):337-41. doi: 10.3109/01485017908988425.
2
[Studies on the detection of antibodies to Neisseria gonorrheae using pilus antigen].
Dermatol Monatsschr. 1989;175(3):163-9.
3
Antibody-antigen specificity in the immune response to infection with Neisseria gonorrhoeae.针对淋病奈瑟菌感染的免疫反应中的抗体-抗原特异性。
J Infect Dis. 1985 Nov;152(5):990-1001. doi: 10.1093/infdis/152.5.990.
4
An indirect haemagglutination test for demonstration of gonococcal antibodies using gonococcal pili as antigen. II. Serological investigation of patients attending a dermato-venereological outpatients clinic in Copenhagen.以淋球菌菌毛为抗原检测淋球菌抗体的间接血凝试验。II. 哥本哈根一家皮肤性病门诊患者的血清学调查
Acta Pathol Microbiol Scand C. 1980 Jun;88(3):155-62. doi: 10.1111/j.1699-0463.1980.tb00089.x.
5
Enzyme-linked immunosorbent assay for detecting gonococcal antibodies using two antigenically different gonococcal pili as antigen.使用两种抗原性不同的淋球菌菌毛作为抗原的酶联免疫吸附测定法检测淋球菌抗体。
Br J Vener Dis. 1983 Apr;59(2):89-91. doi: 10.1136/sti.59.2.89.
6
[Serodiagnosis of gonorrhea].[淋病的血清学诊断]
Hautarzt. 1980 May;31(5):251-4.
7
Diagnosis of Neisseria gonorrhoeae and Chlamydia trachomatis infections using antigen detection methods.使用抗原检测方法诊断淋病奈瑟菌和沙眼衣原体感染。
Diagn Microbiol Infect Dis. 1986 Mar;4(3 Suppl):93S-99S. doi: 10.1016/s0732-8893(86)80047-5.
8
Indirect haemagglutination test using gonococcal pilus antigen: how useful to diagnose gonorrhoea?使用淋球菌菌毛抗原的间接血凝试验:对诊断淋病有多大用处?
Genitourin Med. 1987 Aug;63(4):250-5. doi: 10.1136/sti.63.4.250.
9
Antibodies to gonococcal pili in women with asymptomatic gonorrhoea. Diagnostic value of the ELISA for testing women attending an STD clinic.无症状淋病女性中针对淋球菌菌毛的抗体。酶联免疫吸附测定法(ELISA)对性病门诊就诊女性进行检测的诊断价值。
Br J Vener Dis. 1983 Apr;59(2):85-8. doi: 10.1136/sti.59.2.85.
10
Evaluation of a rapid antigen detection test for Neisseria gonorrhoeae in urine sediment for diagnosis of gonococcal urethritis in males.尿液沉渣中淋病奈瑟菌快速抗原检测试验用于男性淋菌性尿道炎诊断的评估
J Infect Chemother. 2004 Aug;10(4):208-11. doi: 10.1007/s10156-004-0322-6.

引用本文的文献

1
Radioimmunoassay for detection of antibodies to Neisseria gonorrhoeae.用于检测淋病奈瑟菌抗体的放射免疫测定法。
J Clin Microbiol. 1982 Jun;15(6):1001-8. doi: 10.1128/jcm.15.6.1001-1008.1982.
2
Indirect haemagglutination test using gonococcal pilus antigen: how useful to diagnose gonorrhoea?使用淋球菌菌毛抗原的间接血凝试验:对诊断淋病有多大用处?
Genitourin Med. 1987 Aug;63(4):250-5. doi: 10.1136/sti.63.4.250.