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一种卵巢细胞生长因子的生物活性。

Biological activity of a growth factor for ovarian cells.

作者信息

Jones K L, Gospodarowicz D

出版信息

Proc Natl Acad Sci U S A. 1974 Sep;71(9):3372-6. doi: 10.1073/pnas.71.9.3372.

DOI:10.1073/pnas.71.9.3372
PMID:4372617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC433774/
Abstract

The biological activity of a protein growth factor is described. This factor was isolated from bovine pituitary tissue, and its activity was tested on cells of rat ovarian origin. Activity was assayed as growth-promoting potential measured by cell counts and is concentrationdependent. Similar growth stimulation was not produced by several cyclic nucleotides tested, neither was there crossreactivity between this growth factor and a chemically similar one produced by rat liver cells.

摘要

描述了一种蛋白质生长因子的生物活性。该因子从牛垂体组织中分离出来，其活性在大鼠卵巢来源的细胞上进行了测试。活性通过细胞计数测定的促生长潜力来评估，且呈浓度依赖性。所测试的几种环核苷酸未产生类似的生长刺激作用，该生长因子与大鼠肝细胞产生的化学结构相似的因子之间也没有交叉反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8de/433774/23aa779c58e1/pnas00072-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8de/433774/23aa779c58e1/pnas00072-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8de/433774/23aa779c58e1/pnas00072-0059-a.jpg

相似文献

1
Biological activity of a growth factor for ovarian cells.一种卵巢细胞生长因子的生物活性。
Proc Natl Acad Sci U S A. 1974 Sep;71(9):3372-6. doi: 10.1073/pnas.71.9.3372.
2
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引用本文的文献

1
Control of ovarian cell growth in culture by serum and pituitary factors.血清和垂体因子对培养的卵巢细胞生长的控制
Proc Natl Acad Sci U S A. 1975 Feb;72(2):483-7. doi: 10.1073/pnas.72.2.483.
2
Hormonal control of adrenocortical cell proliferation. Desensitization to ACTH and interaction between ACTH and fibroblast growth factor in bovine adrenocortical cell cultures.
J Clin Invest. 1977 Aug;60(2):342-52. doi: 10.1172/JCI108782.
3
Fibroblast and epidermal growth factors: their uses in vivo and in vitro in studies on cell functions and cell transplantation.
Mol Cell Biochem. 1979 May 21;25(2):79-110. doi: 10.1007/BF00228991.

本文引用的文献

1
The presence of a common type of subunit in bovine thyroid-stimulating and luteinizing hormones.牛促甲状腺激素和促黄体生成激素中一种常见亚基的存在。
J Biol Chem. 1970 Jul 10;245(13):3275-81.
2
"Pleiotypic response".多型性反应
Nat New Biol. 1971 Aug;232(33):206-11.
3
Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts.正常及猿猴病毒40转化的3T3小鼠成纤维细胞的血清因子需求
Proc Natl Acad Sci U S A. 1971 Mar;68(3):645-52. doi: 10.1073/pnas.68.3.645.
4
"Contact inhibition" of cell division in 3T3 cells.3T3细胞中细胞分裂的“接触抑制”
Proc Natl Acad Sci U S A. 1968 May;60(1):300-4. doi: 10.1073/pnas.60.1.300.
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Amino acid sequence of a biologically active fragment of bovine growth hormone.牛生长激素生物活性片段的氨基酸序列
J Biol Chem. 1972 Jun 25;247(12):3874-80.
6
A pituitary growth-promoting factor for articular chondrocytes in monolayer culture.单层培养中关节软骨细胞的一种垂体生长促进因子。
Endocrinology. 1972 Jan;90(1):262-71. doi: 10.1210/endo-90-1-262.
7
Nerve growth factor and insulin.神经生长因子与胰岛素。
Science. 1972 May 5;176(4034):482-8. doi: 10.1126/science.176.4034.482.
8
Multiplication-stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: a family of small polypeptides.来自大鼠肝细胞条件培养基的鸡胚成纤维细胞增殖刺激活性：一族小多肽。
J Cell Physiol. 1973 Apr;81(2):161-70. doi: 10.1002/jcp.1040810205.
9
A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication-stimulating activity for embryo fibroblasts.一种从大鼠肝细胞条件培养液中获得的部分纯化的多肽组分，对胚胎成纤维细胞具有增殖刺激活性。
J Cell Physiol. 1973 Apr;81(2):153-60. doi: 10.1002/jcp.1040810204.
10
Single step purification of ovine luteinizing hormone by affinity chromatography.
J Biol Chem. 1972 Oct 25;247(20):6491-8.