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Proc Natl Acad Sci U S A. 1971 Mar;68(3):645-52. doi: 10.1073/pnas.68.3.645.
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Differential growth factor expression in transformed mouse NIH-3T3 cells.转化的小鼠NIH-3T3细胞中生长因子的差异表达。
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Proc Natl Acad Sci U S A. 1972 Jan;69(1):109-14. doi: 10.1073/pnas.69.1.109.

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TRANSFORMATION OF PROPERTIES OF AN ESTABLISHED CELL LINE BY SV40 AND POLYOMA VIRUS.SV40和多瘤病毒对已建细胞系特性的转化
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Nutrition needs of mammalian cells in tissue culture.组织培养中哺乳动物细胞的营养需求。
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"Contact inhibition" of cell division in 3T3 cells.3T3细胞中细胞分裂的“接触抑制”
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Topoinhibition and serum requirement of transformed and untransformed cells.转化细胞和未转化细胞的拓扑抑制及血清需求
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Requirement of serum for DNA synthesis in BHK 21 cells: effects of density, suspension and virus transformation.血清对BHK 21细胞DNA合成的需求：密度、悬浮培养及病毒转化的影响
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Surface-specific characteristics of a contact-inhibited cell line containing the SV40 viral genome.含有SV40病毒基因组的接触抑制细胞系的表面特异性特征。
Proc Natl Acad Sci U S A. 1969 Apr;62(4):1074-6. doi: 10.1073/pnas.62.4.1074.
9
Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability.培养细胞中的生长控制：对接触抑制敏感性增加且肿瘤产生能力降低的亚系的选择。
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10
Stimulation of cell growth in vitro by serum with and without growth factor. Relation to contact inhibition and viral transformation.含生长因子和不含生长因子的血清对体外细胞生长的刺激作用。与接触抑制和病毒转化的关系。
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正常及猿猴病毒40转化的3T3小鼠成纤维细胞的血清因子需求

Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts.

作者信息

Paul D, Lipton A, Klinger I

出版信息

Proc Natl Acad Sci U S A. 1971 Mar;68(3):645-52. doi: 10.1073/pnas.68.3.645.

DOI:10.1073/pnas.68.3.645
PMID:5276775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC389008/
Abstract

Evidence is presented to show the presence in normal rat serum of four different serum factors essential for growth of 3T3 or SV40-transformed 3T3 mouse fibroblasts: a factor that specifically promotes growth of normal 3T3 cells; two factors that specifically promote growth of transformed 3T3 cells; and a factor that sustains viability of both normal and transformed 3T3 cells in serum-free medium, probably without inducing growth of the cells. These factors are separated and partially purified.

摘要

有证据表明，正常大鼠血清中存在四种对3T3或SV40转化的3T3小鼠成纤维细胞生长至关重要的不同血清因子：一种特异性促进正常3T3细胞生长的因子；两种特异性促进转化的3T3细胞生长的因子；以及一种在无血清培养基中维持正常和转化的3T3细胞活力的因子，可能不会诱导细胞生长。这些因子被分离并部分纯化。