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Synthesis and accumulation of triglycerides in liver of diabetic rats. Effects of insulin treatment.

作者信息

Murthy V K, Shipp J C

出版信息

Diabetes. 1979 May;28(5):472-8. doi: 10.2337/diab.28.5.472.

DOI:10.2337/diab.28.5.472
PMID:437376
Abstract
摘要

相似文献

1
Synthesis and accumulation of triglycerides in liver of diabetic rats. Effects of insulin treatment.糖尿病大鼠肝脏中甘油三酯的合成与积累。胰岛素治疗的效果。
Diabetes. 1979 May;28(5):472-8. doi: 10.2337/diab.28.5.472.
2
Heart triglyceride synthesis in diabetes: selective increase in activity of enzymes of phosphatidate synthesis.糖尿病患者心脏甘油三酯合成：磷脂酸合成酶活性选择性增加。
J Mol Cell Cardiol. 1980 Mar;12(3):299-309. doi: 10.1016/0022-2828(80)90042-5.
3
Enhancement of microsomal phosphatidate phosphohydrolase and diacylglycerol acyltransferase activity by insulin during growth of rat adipocyte precursors in culture.在培养的大鼠脂肪细胞前体生长过程中胰岛素对微粒体磷脂酸磷酸水解酶和二酰基甘油酰基转移酶活性的增强作用。
Can J Biochem. 1979 Jun;57(6):573-7. doi: 10.1139/o79-072.
4
Hepatic steatosis in diabetes: increased synthesis of triacylglycerol and impaired feedback regulation.糖尿病中的肝脂肪变性：三酰甘油合成增加及反馈调节受损。
Trans Assoc Am Physicians. 1981;94:322-32.
5
Effects of streptozotocin-diabetes and insulin administration in vivo or in vitro on the activities of five enzymes in the adipose-tissue triacylglycerol-synthesis pathway.链脲佐菌素诱导的糖尿病及体内或体外给予胰岛素对脂肪组织三酰甘油合成途径中五种酶活性的影响。
Biochem J. 1987 Apr 1;243(1):289-92. doi: 10.1042/bj2430289.
6
Regulation of hepatic triglyceride synthesis in diabetic rats.糖尿病大鼠肝脏甘油三酯合成的调节
J Clin Invest. 1981 Apr;67(4):923-30. doi: 10.1172/jci110141.
7
Enzymes of glycerolipid synthesis in eukaryotes.真核生物中甘油脂质合成的酶。
Annu Rev Biochem. 1980;49:459-87. doi: 10.1146/annurev.bi.49.070180.002331.
8
Interactions of insulin, glucagon and dexamethasone in controlling the activity of glycerol phosphate acyltransferase and the activity and subcellular distribution of phosphatidate phosphohydrolase in cultured rat hepatocytes.胰岛素、胰高血糖素和地塞米松在调控培养大鼠肝细胞中磷酸甘油酰基转移酶活性以及磷脂酸磷酸水解酶活性和亚细胞分布方面的相互作用。
Biochem J. 1985 Sep 1;230(2):525-34. doi: 10.1042/bj2300525.
9
Control of hepatic triacylglycerol synthesis. Diurnal variations in hepatic phosphatidate phosphohydrolase activity and in the concentrations of circulating insulin and corticosterone in rats.肝脏三酰甘油合成的调控。大鼠肝脏磷脂酸磷酸水解酶活性以及循环胰岛素和皮质酮浓度的昼夜变化。
Biochem J. 1979 May 15;180(2):441-3. doi: 10.1042/bj1800441.
10
Effects of insulin treatment on ketone body production and carnitine-palmitoyl-transferase (CPT) activity in the isolated perfused liver from streptozotocin diabetic rats.胰岛素治疗对链脲佐菌素诱导的糖尿病大鼠离体灌注肝脏中酮体生成及肉碱-棕榈酰转移酶（CPT）活性的影响。
Horm Metab Res. 1985 Jun;17(6):271-4. doi: 10.1055/s-2007-1013517.

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Study of blood glucose and insulin infusion rate in real-time in diabetic rats using an artificial pancreas system.利用人工胰腺系统实时研究糖尿病大鼠的血糖和胰岛素输注率。
PLoS One. 2021 Jul 16;16(7):e0254718. doi: 10.1371/journal.pone.0254718. eCollection 2021.
2
Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance.整合素连接激酶是饮食诱导的肝胰岛素抵抗发生所必需的。
Diabetes. 2017 Feb;66(2):325-334. doi: 10.2337/db16-0484. Epub 2016 Nov 29.
3
Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance.
整合素α1基因敲除小鼠在喂食高脂饮食时，尽管存在严重的肝脏胰岛素抵抗，但脂肪肝情况仍有所改善。
J Biol Chem. 2015 Mar 6;290(10):6546-57. doi: 10.1074/jbc.M114.615716. Epub 2015 Jan 15.
4
Linoleic acid metabolism in the spontaneously diabetic rat: delta6-desaturase activity vs. product/precursor ratios.自发性糖尿病大鼠的亚油酸代谢：Δ6-去饱和酶活性与产物/前体比率
Lipids. 2000 Dec;35(12):1319-23. doi: 10.1007/s11745-000-0648-1.
5
Effect of selenium and vitamin E supplements on tissue lipids, peroxides, and fatty acid distribution in experimental diabetes.硒和维生素E补充剂对实验性糖尿病中组织脂质、过氧化物及脂肪酸分布的影响
Lipids. 1998 Apr;33(4):393-9. doi: 10.1007/s11745-998-0220-z.
6
Triacylglycerol metabolism in the phenobarbital-treated rat.苯巴比妥处理的大鼠中的三酰甘油代谢
Biochem J. 1981 Apr 15;196(1):337-46. doi: 10.1042/bj1960337.
7
Effects of phenobarbital upon triacylglycerol metabolism in the rabbit.苯巴比妥对家兔甘油三酯代谢的影响。
Biochem J. 1980 Oct 15;192(1):165-75. doi: 10.1042/bj1920165.
8
Regulation of hepatic triglyceride synthesis in diabetic rats.糖尿病大鼠肝脏甘油三酯合成的调节
J Clin Invest. 1981 Apr;67(4):923-30. doi: 10.1172/jci110141.
9
Inhibition by adenosine triphosphate of heart microsomal neutral lipase activity.三磷酸腺苷对心脏微粒体中性脂肪酶活性的抑制作用。
Lipids. 1983 Jun;18(6):408-11. doi: 10.1007/BF02535426.
10
Effects of dexamethasone and insulin on the synthesis of triacylglycerols and phosphatidylcholine and the secretion of very-low-density lipoproteins and lysophosphatidylcholine by monolayer cultures of rat hepatocytes.地塞米松和胰岛素对大鼠肝细胞单层培养物中三酰甘油和磷脂酰胆碱合成以及极低密度脂蛋白和溶血磷脂酰胆碱分泌的影响。
Biochem J. 1986 Jan 1;233(1):151-60. doi: 10.1042/bj2330151.