Dudenhausen J W, Meinhold H, Kynast G
Fortschr Med. 1979 Jun 7;97(21):1001-3.
In the present study we tried to find out relationships between lung maturation-assessable by aid of lecithin concentrations in amniotic fluid-and fetal thyreoid gland function. In 256 pregnant women amniocentesis was done after 31/0 weeks of gestation, and concentrations of thyroxin, of reverse triiodothyronine and lecithins were measured. While thyroxin and lecithin concentrations proved not to be correlated, the rT3 and lecithin concentrations showed significant correlation (2 p less than 0.001). The curves measured were interpreted as signs of maturity of various organs (lung, thyreoid gland). We found out, that clinical value of measuring thyreoid gland hormones in relation to diagnosis of fetal maturation is of less importance.
在本研究中,我们试图找出借助羊水卵磷脂浓度评估的肺成熟度与胎儿甲状腺功能之间的关系。对256名孕妇在妊娠31/0周后进行了羊膜穿刺术,并测量了甲状腺素、反三碘甲状腺原氨酸和卵磷脂的浓度。虽然甲状腺素和卵磷脂浓度被证明没有相关性,但反三碘甲状腺原氨酸和卵磷脂浓度显示出显著相关性(P<0.001)。所测得的曲线被解释为各器官(肺、甲状腺)成熟的标志。我们发现,就胎儿成熟度诊断而言,测量甲状腺激素的临床价值不太重要。