Adinolfi M
Immunology. 1965 Jul;9(1):31-42.
The finding that the presence of normal incomplete cold antibody in cord serum is independent of its presence in the corresponding maternal sample suggests that the antibody is produced by the newborn infant. The observation that the antibody has a constant titre in newborn infants aged between a few weeks and 6 months points to the same conclusion. The normal incomplete cold antibody differs from other blood group antibodies in its thermolability, in being present in the serum of patients with severe hypogammaglobulinaemia and in its interaction with some polysaccharides and bacteria. In many respects the antibody resembles properdin, but markedly differs from properdin in its specificity and other serological characteristics.
脐血清中存在正常不完全冷抗体与其相应母体样本中该抗体的存在无关,这一发现表明该抗体是由新生儿产生的。在几周至6个月大的新生儿中,该抗体具有恒定滴度的观察结果也指向了相同的结论。正常不完全冷抗体在热稳定性、存在于严重低丙种球蛋白血症患者的血清中以及与某些多糖和细菌的相互作用方面与其他血型抗体不同。在许多方面,该抗体类似于备解素,但在特异性和其他血清学特征方面与备解素明显不同。