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性激素对患有莫里斯肝癌5123 D的大鼠血清中γ-谷氨酰转肽酶活性的影响。

Influence of sex hormones on gamma-glutamyltranspeptidase activity in rats serum with Morris hepatoma 5123 D.

作者信息

Albert M

出版信息

Folia Histochem Cytochem (Krakow). 1979;17(4):363-70.

PMID:43820
Abstract

The Stilbestrol treatment of the female rats with the Morris hepatoma 5123 D resulted in decrease of the gamma-glutamyl-transpeptidase (GGTP) activity in serum and in hepatoma, but only during the treatment. Given to the male rats under the same conditions, Stilbestrol had no influence on the GGTP activity. Castration of males was the cause of the GGTP activity decay in hepatoma and in serum, but it was not the case with females. Sustanon diminished the GGTP activity in serum of the female rats with hepatoma.

摘要

用己烯雌酚治疗患有莫里斯肝癌5123D的雌性大鼠,会导致血清和肝癌组织中的γ-谷氨酰转肽酶(GGTP)活性降低,但仅在治疗期间如此。在相同条件下对雄性大鼠给予己烯雌酚,其对GGTP活性没有影响。雄性大鼠去势是肝癌组织和血清中GGTP活性下降的原因,但雌性大鼠并非如此。长效多睾酮降低了患有肝癌的雌性大鼠血清中的GGTP活性。

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