• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

家禽肠系膜前动脉纵行肌中神经递质的自发释放和诱发释放

Spontaneous and evoked release of neurotransmitter substances in the longitudinal muscle of the anterior mesenteric artery of the domestic fowl.

作者信息

Bolton T B

出版信息

Br J Pharmacol. 1969 Jan;35(1):112-20. doi: 10.1111/j.1476-5381.1969.tb07971.x.

DOI:10.1111/j.1476-5381.1969.tb07971.x
PMID:4387391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1703086/
Abstract
  1. Changes in length of the longitudinal muscle of the anterior mesenteric artery of the domestic fowl (LMAMA) were recorded isotonically.2. The actions of physostigmine and hyoscine suggest that the tone of the LMAMA is dependent on a resting release of acetylcholine within the tissue.3. Catecholamines inhibited the contractions obtained in response to stimulation of cholinergic nerves; this was a beta-receptor effect. After beta-receptor blockade, noradrenaline, but not isoprenaline, weakly facilitated the effects of stimulating cholinergic nerves.4. In the presence of hyoscine, nicotine relaxed preparations of the LMAMA in which the tone had been raised with barium chloride. These relaxations were considered to be due to a release of catecholamine probably from sympathetic nerves.
摘要

  1. 以等张方式记录家鸡肠系膜前动脉纵行肌（LMAMA）的长度变化。

  2. 毒扁豆碱和东莨菪碱的作用表明，LMAMA的张力取决于组织内乙酰胆碱的静息释放。

  3. 儿茶酚胺抑制了对胆碱能神经刺激所产生的收缩；这是一种β受体效应。β受体阻断后，去甲肾上腺素而非异丙肾上腺素，对刺激胆碱能神经的效应有微弱的促进作用。

  4. 在存在东莨菪碱的情况下，尼古丁使已用氯化钡提高张力的LMAMA标本松弛。这些松弛被认为可能是由于交感神经释放儿茶酚胺所致。

相似文献

1
Spontaneous and evoked release of neurotransmitter substances in the longitudinal muscle of the anterior mesenteric artery of the domestic fowl.家禽肠系膜前动脉纵行肌中神经递质的自发释放和诱发释放
Br J Pharmacol. 1969 Jan;35(1):112-20. doi: 10.1111/j.1476-5381.1969.tb07971.x.
2
Studies on the longitudinal muscle of the anterior mesentric artery of the domestic fowl.家鸡肠系膜前动脉纵行肌的研究。
J Physiol. 1968 May;196(2):273-81. doi: 10.1113/jphysiol.1968.sp008506.
3
Electrical and mechanical activity of the longitudinal muscle of the anterior mesenteric artery of the domestic fowl.家鸡肠系膜前动脉纵行肌的电活动和机械活动
J Physiol. 1968 May;196(2):283-92. doi: 10.1113/jphysiol.1968.sp008507.
4
Evidence for inhibition of sympathetic neurotransmission by endogenously released acetylcholine in the guinea-pig trachea.豚鼠气管中内源性释放的乙酰胆碱对交感神经传递的抑制作用的证据。
Br J Pharmacol. 1991 Dec;104(4):817-22. doi: 10.1111/j.1476-5381.1991.tb12512.x.
5
Inhibitory responses to nicotine and transmural stimulation in hyoscine-treated guinea-pig isolated trachealis: an electrical and mechanical study.东莨菪碱处理的豚鼠离体气管对尼古丁和跨壁刺激的抑制反应：电生理和力学研究
Br J Pharmacol. 1987 Apr;90(4):733-44. doi: 10.1111/j.1476-5381.1987.tb11227.x.
6
Studies on the responses of the isolated rectum of domestic chick (Gallus domesticus) to drugs.家鸡（原鸡）离体直肠对药物反应的研究。
Biochem Exp Biol. 1980;16(4):413-20.
7
Relaxations of the isolated portal vein of the rabbit induced by nicotine and electrical stimulation.尼古丁和电刺激对兔离体门静脉的舒张作用
Br J Pharmacol. 1970 Jul;39(3):476-89. doi: 10.1111/j.1476-5381.1970.tb10356.x.
8
THE PART PLAYED BY CALCIUM IN DETERMINING THE RESPONSE TO STIMULATION OF SYMPATHETIC POSTGANGLIONIC FIBRES.钙在决定交感神经节后纤维对刺激的反应中所起的作用。
Br J Pharmacol Chemother. 1964 Jun;22(3):540-8. doi: 10.1111/j.1476-5381.1964.tb01708.x.
9
Inhibition of gastrointestinal movement by sympathetic nerve stimulation: the site of action.交感神经刺激对胃肠运动的抑制作用：作用部位。
J Physiol. 1967 Apr;189(2):317-27. doi: 10.1113/jphysiol.1967.sp008170.
10
Characteristics of the internal anal sphincter and the rectum of the vervet monkey.绿猴肛门内括约肌和直肠的特征
J Physiol. 1979 Jan;286:383-99. doi: 10.1113/jphysiol.1979.sp012627.

引用本文的文献

1
Development of longitudinal smooth muscle in the posterior mesenteric artery and purinergic regulation of its contractile responses in chickens.鸡的后肠系膜动脉纵向平滑肌的发育及其收缩反应的嘌呤能调节。
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2013 Oct;199(10):857-65. doi: 10.1007/s00359-013-0848-0. Epub 2013 Aug 21.
2
P2X purinoceptors mediate an endothelium-dependent hyperpolarization in longitudinal smooth muscle of anterior mesenteric artery in young chickens.P2X嘌呤受体介导幼鸡肠系膜前动脉纵行平滑肌的内皮依赖性超极化。
Br J Pharmacol. 2009 Oct;158(3):888-95. doi: 10.1111/j.1476-5381.2009.00356.x. Epub 2009 Aug 19.
3
Neurally released ATP mediates endothelium-dependent hyperpolarization in the circular smooth muscle cells of chicken anterior mesenteric artery.神经释放的三磷酸腺苷介导鸡肠系膜前动脉环形平滑肌细胞的内皮依赖性超极化。
Br J Pharmacol. 2005 Dec;146(7):983-9. doi: 10.1038/sj.bjp.0706413.
4
An electrophysiological study of excitatory purinergic neuromuscular transmission in longitudinal smooth muscle of chicken anterior mesenteric artery.鸡肠系膜前动脉纵行平滑肌中兴奋性嘌呤能神经肌肉传递的电生理研究。
Br J Pharmacol. 2005 Mar;144(6):830-9. doi: 10.1038/sj.bjp.0706076.

本文引用的文献

1
The spontaneous release of acetylcholine from the denervated hemidiaphragm of the rat.大鼠去神经支配半膈肌中乙酰胆碱的自发释放。
J Physiol. 1963 Jan;165(1):117-29. doi: 10.1113/jphysiol.1963.sp007046.
2
The effect of cocaine on the acetylcholine output of the intestinal wall.可卡因对肠壁乙酰胆碱分泌量的影响。
J Physiol. 1949 Sep;109(3-4):475-87. doi: 10.1113/jphysiol.1949.sp004410.
3
A ganglion stimulating action of neostigmine.新斯的明的神经节刺激作用。
Br J Pharmacol Chemother. 1962 Feb;18(1):76-86. doi: 10.1111/j.1476-5381.1962.tb01152.x.
4
Action of nicotine on the rabbit muscular organ (ileo-colic sphincter).尼古丁对家兔肌肉器官（回盲括约肌）的作用。
Br J Pharmacol Chemother. 1962 Apr;18(2):397-404. doi: 10.1111/j.1476-5381.1962.tb01419.x.
5
THE EFFECTS ON CARDIAC MUSCLE OF BETA-RECEPTOR ANTAGONISTS IN RELATION TO THEIR ACTIVITY AS LOCAL ANAESTHETICS.β受体拮抗剂对心肌的作用与其作为局部麻醉剂的活性的关系。
Br J Pharmacol Chemother. 1965 Apr;24(2):332-8. doi: 10.1111/j.1476-5381.1965.tb01719.x.
6
THE RESPONSES OF THE GUINEA-PIG ISOLATED INTACT TRACHEA TO TRANSMURAL STIMULATION AND THE RELEASE OF AN ACETYLCHOLINE-LIKE SUBSTANCE UNDER CONDITIONS OF REST AND STIMULATION.豚鼠离体完整气管对跨壁刺激的反应以及在静息和刺激条件下类乙酰胆碱物质的释放
Br J Pharmacol Chemother. 1964 Feb;22(1):126-36. doi: 10.1111/j.1476-5381.1964.tb01550.x.
7
THE MODE OF ACTION OF NEOSTIGMINE AND PHYSOSTIGMINE ON THE GUINEA-PIG TRACHEALIS MUSCLE.新斯的明和毒扁豆碱对豚鼠气管平滑肌的作用方式。
Br J Pharmacol Chemother. 1963 Aug;21(1):137-49. doi: 10.1111/j.1476-5381.1963.tb01509.x.
8
A comparison between the effects of a tetanus and the effects of sympathomimetic amines on fast- and slow-contracting mammalian muscles.破伤风毒素与拟交感胺对哺乳动物快收缩和慢收缩肌肉作用的比较。
Br J Pharmacol Chemother. 1962 Dec;19(3):464-84. doi: 10.1111/j.1476-5381.1962.tb01451.x.
9
Analysis of he responses of the isolated stomach to electrical stimulation and to drugs.对离体胃对电刺激和药物反应的分析。
J Physiol. 1963 Jan;165(1):10-46. doi: 10.1113/jphysiol.1963.sp007040.
10
Actions of some anticholinesterases on the smooth muscle of the chick amnion.某些抗胆碱酯酶对鸡羊膜平滑肌的作用。
Br J Pharmacol Chemother. 1962 Jun;18(3):550-62. doi: 10.1111/j.1476-5381.1962.tb01174.x.