Fishman B, Wurtman R J, Munro H N
Proc Natl Acad Sci U S A. 1969 Oct;64(2):677-82. doi: 10.1073/pnas.64.2.677.
Hepatic polysome profiles vary in untreated rats as a function of time of day. The ratio of polysomes to total ribosomes increases from 50 to 73 per cent in darkness. There is also a daily rhythm in tyrosine transaminase activity which resembles but does not coincide with the polysome rhythm. Both rhythms are dependent on the cyclic ingestion of dietary protein, and disappear in rats given a protein-free diet.
未处理的大鼠肝脏多核糖体图谱随一天中的时间而变化。在黑暗中，多核糖体与总核糖体的比例从50%增加到73%。酪氨酸转氨酶活性也存在日节律，其与多核糖体节律相似但不一致。两种节律均依赖于膳食蛋白质的周期性摄入，在给予无蛋白饮食的大鼠中消失。
