Pantell R H, Stewart T J
JAMA. 1979 May 25;241(21):2272-4.
A new polyvalent pneumococcal vaccine (Pneumovax) was released in February 1978. In an effort to chronicle the dissemination of the vaccine to high-risk patients, we prospectively followed up a single clinic population and conducted a telephone survey of three neighborhood health centers, two private practices, and a university hematology clinic. Three months after notification of the vaccine arrival, physicians in the prospectively chronicled clinic had immunized six of 12 patients with sickle cell disease, five of 80 patients with chronic obstructive pulmonary disease, three of 225 patients with diabetes, and three of 45 patients older than 80 years. Immunization policy in the other clinics surveyed varied greatly. As an attempt to curb low-prevalence, high-severity illness in a small target population, the pneumococcal vaccine presents a new set of problems in the systematic implementation of an immunization.
一种新的多价肺炎球菌疫苗(肺炎球菌疫苗)于1978年2月发布。为了记录该疫苗在高危患者中的推广情况,我们对一个诊所的患者群体进行了前瞻性随访,并对三个社区卫生中心、两个私人诊所和一个大学血液学诊所进行了电话调查。在通知疫苗到货三个月后,在前瞻性记录的诊所中,医生为12名镰状细胞病患者中的6名、80名慢性阻塞性肺疾病患者中的5名、225名糖尿病患者中的3名以及45名80岁以上患者中的3名进行了免疫接种。接受调查的其他诊所的免疫政策差异很大。作为在小目标人群中控制低流行率、高严重性疾病的一种尝试,肺炎球菌疫苗在免疫接种的系统实施中带来了一系列新问题。