Matsuoka I, Shirakawa K
Jpn J Antibiot. 1979 Mar;32(3):342-5.
CS-1170 was used in gynecological cases of infection, and the following satisfactory results were obtained. 1. The drug was markedly effective in 3 of 12 cases, effective in 7, and ineffective in 2, being the efficacy rate 83.3%. 2. It was highly effective even in the cases in which cefazolin (CEZ) and sulbenicillin (SBPC) were ineffective. 3. The results of the bacteriological examinations turned to negative in 7 cases, but continued to be positive in 2, being the bacteriological efficacy rate 77.7%. It is noteworthy that E. coli completely disappeared by the administration of CS-1170 in 2 cases in which CEZ was ineffective. 4. No side effect attributable to CS-1170 administration was observed.
CS - 1170用于妇科感染病例,并取得了以下令人满意的结果。1. 12例中有3例药物疗效显著,7例有效,2例无效,有效率为83.3%。2. 即使在头孢唑林(CEZ)和磺苄西林(SBPC)无效的病例中,它也非常有效。3. 细菌学检查结果7例转为阴性,但2例仍为阳性,细菌学有效率为77.7%。值得注意的是,在2例CEZ无效的病例中,通过使用CS - 1170,大肠杆菌完全消失。4. 未观察到因使用CS - 1170而产生的副作用。