Liusov V A, Belousov Iu B, Savenkov M P, Sidorskiĭ A L, Panchenko E P
Kardiologiia. 1979 Apr;19(4):86-93.
One hundred and ninety-eight patients with congestive circulatory insufficiency were examined; 54 had stage IIA, 88 stage IIB, and 56 stage III of the disease. Blood viscosity, blood platelet and erythrocyte aggregation, fibrinogen disintegration products, and soluble fibrin were determined and the protamine sulfate test was performed. Statistically significant reduction of hematocrit, increase of erythrocyte aggregation, dysfunction of blood platelets, and increase in the content of products of fibrinogen and fibrin disintegration were revealed with progression of congestive circulatory insufficiency. These changes are evidence of disseminated intravascular coagulation in such patients and are important in prognostication.
对198例充血性循环功能不全患者进行了检查;其中54例处于疾病IIA期,88例处于IIB期,56例处于III期。测定了血液粘度、血小板和红细胞聚集性、纤维蛋白原降解产物以及可溶性纤维蛋白,并进行了硫酸鱼精蛋白试验。结果显示,随着充血性循环功能不全的进展,血细胞比容有统计学意义的降低、红细胞聚集性增加、血小板功能障碍以及纤维蛋白原和纤维蛋白降解产物含量增加。这些变化是此类患者弥散性血管内凝血的证据,对预后判断具有重要意义。