核酸与蛋白质相互作用的模型研究：酰胺与核酸碱基的氢键作用。
Model studies of interactions between nucleic acids and proteins: hydrogen bonding of amides with nucleic acid bases.
作者信息
Lancelot G, Hélène C
出版信息
Nucleic Acids Res. 1979 Mar;6(3):1063-71. doi: 10.1093/nar/6.3.1063.
Abstract
The formation of hydrogen bonded complexes between nucleic acid bases and acetamide has been studied by nuclear magnetic resonance in CDC13 at different temperatures. Pairs of hydrogen bonds are formed when acetamide binds to nucleic acid bases. Thermodynamic parameters have been computed and compared to those obtained for the association of carboxylic acids with nucleic acid bases. The role of hydrogen bonded complexes in the association of proteins with nucleic acids is discussed.
摘要
通过在不同温度下于CDCl₃中进行核磁共振研究了核酸碱基与乙酰胺之间氢键复合物的形成。当乙酰胺与核酸碱基结合时会形成氢键对。已计算出热力学参数，并与羧酸与核酸碱基缔合所获得的参数进行了比较。讨论了氢键复合物在蛋白质与核酸缔合中的作用。
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本文引用的文献
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Hydrogen bonding of amino acid side chains to nucleic acid bases.氨基酸侧链与核酸碱基之间的氢键作用。
FEBS Lett. 1973 Mar 1;30(2):219-224. doi: 10.1016/0014-5793(73)80655-6.
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Hydrogen bonding of secondary amides.
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An infrared study of hydrogen bonding between adenine and uracil derivatives in chloroform solution.氯仿溶液中腺嘌呤与尿嘧啶衍生物之间氢键的红外光谱研究。
J Am Chem Soc. 1967 Feb 1;89(3):496-504. doi: 10.1021/ja00979a005.
4
Sequence-specific recognition of double helical nucleic acids by proteins.蛋白质对双螺旋核酸的序列特异性识别。
Proc Natl Acad Sci U S A. 1976 Mar;73(3):804-8. doi: 10.1073/pnas.73.3.804.
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Hydrogen bonding of amino acid side chains to nucleic acid bases.
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Hydrogen bonding between nucleic acid bases and carboxylic acids.
J Am Chem Soc. 1977 Oct 12;99(21):7037-42. doi: 10.1021/ja00463a044.
7
Selective recognition of nucleic acids by proteins: the specificity of guanine interaction with carboxylate ions.蛋白质对核酸的选择性识别：鸟嘌呤与羧酸根离子相互作用的特异性
Proc Natl Acad Sci U S A. 1977 Nov;74(11):4872-5. doi: 10.1073/pnas.74.11.4872.
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