烟草中的N'-亚硝基降烟碱
N'-nitrosonornicotine in tobacco.
作者信息
Hoffmann D, Hecht S S, Ornaf R M, Wynder E L
出版信息
Science. 1974 Oct 18;186(4160):265-7. doi: 10.1126/science.186.4160.265.
PMID:4414773
Abstract
N'-Nitrosonornicotine, a potential carcinogen, has been positively identified in unburned tobacco. The amount in commercial U.S. tobacco products is between 1.9 to 88.6 parts per million, one of the highest values of an environmental nitrosamine yet reported. The amount in food and drink rarely exceeds 0.1 part per million. This compound is the first example of a potential organic carcinogen isolated from tobacco.
摘要
N'-亚硝基降烟碱是一种潜在致癌物，已在未燃烧的烟草中被明确鉴定出来。美国商业烟草产品中的含量在百万分之1.9至88.6之间，是迄今报道的环境亚硝胺中含量最高的值之一。食品和饮料中的含量很少超过百万分之0.1。这种化合物是从烟草中分离出的潜在有机致癌物的首个实例。
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