Prunell A, Kornberg R D, Lutter L, Klug A, Levitt M, Crick F H
Science. 1979 May 25;204(4395):855-8. doi: 10.1126/science.441739.
Two methods have been used to measure the single-strand lengths of the DNA fragments produced by deoxyribonuclease I digestion of chromatin. The average lengths obtained are muliples of about 10.4 bases, significantly different from the value of 10 previously reported. This periodicity in fragment lengths is closely related to the periodicity of the DNA double helix in chromatin, but the two values need not be exactly the same.
已使用两种方法来测量由脱氧核糖核酸酶I消化染色质产生的DNA片段的单链长度。所获得的平均长度约为10.4个碱基的倍数，与先前报道的10的值显著不同。片段长度的这种周期性与染色质中DNA双螺旋的周期性密切相关，但这两个值不一定完全相同。
