核酸酶以100个核苷酸对的间隔切割染色质。
Nuclease cleavage of chromatin at 100-nucleotide pair intervals.
作者信息
Altenburger W, Hörz W, Zachau H G
出版信息
Nature. 1976 Dec 9;264(5586):517-22. doi: 10.1038/264517a0.
DOI:10.1038/264517a0
PMID:1004586
Abstract
Digestion of mouse liver nuclei with DNase II leads to a novel cleavage pattern with a 100-nucleotide pair periodicity. From chromatin, this pattern or the standard 200-nucleotide pair repeat can be produced depending on the ionic conditions. The results are interpreted by assuming different conformational states of the nuclear material, including condensed and extended forms.
摘要
用脱氧核糖核酸酶II消化小鼠肝细胞核会产生一种具有100个核苷酸对周期性的新型切割模式。在染色质中，根据离子条件可以产生这种模式或标准的200个核苷酸对重复模式。通过假设核物质的不同构象状态，包括浓缩和伸展形式来解释这些结果。
Zotero 插件