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人体甲状腺激素对长期寒冷暴露的反应。

Thyroid hormone response to prolonged cold exposure in man.

作者信息

Eastman C J, Ekins R P, Leith I M, Williams E S

出版信息

J Physiol. 1974 Aug;241(1):175-81. doi: 10.1113/jphysiol.1974.sp010647.

Abstract
  1. Four men, of ages varying from 23 to 28 years, living at Halley Bay, Antarctica (75 degrees 31' S, 26 degrees 39' W), were exposed to a mean air temperature of 6.6 degrees C.2. The concentration of serum triiodothyronine (T(3)) rose significantly by the second day, remained raised, and returned to pre-exposure levels within 2 days of return to a normal environment.3. The concentration of serum thyroxine (T(4)) rose more slowly than did the T(3), reaching a maximum in 3-4 days and also returning to normal within 2 days of return to a normal environment.4. There was a wide individual variation in the change of concentration of serum cortisol.
摘要
  1. 四名年龄在23至28岁之间的男子居住在南极洲哈雷湾(南纬75度31分,西经26度39分),他们暴露在平均气温为6.6摄氏度的环境中。

  2. 血清三碘甲状腺原氨酸(T₃)浓度在第二天显著升高,持续升高,并在回到正常环境后2天内恢复到暴露前水平。

  3. 血清甲状腺素(T₄)浓度的升高比T₃慢,在3 - 4天达到最高值,同样在回到正常环境后2天内恢复正常。

  4. 血清皮质醇浓度变化存在很大的个体差异。

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