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J Physiol. 1966 Sep;186(1):233-42. doi: 10.1113/jphysiol.1966.sp008031.
2
Cardiovascular and metabolic responses to noradrenaline in men acclimatized to cold baths.适应冷水浴的男性对去甲肾上腺素的心血管和代谢反应。
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Body temperature, shivering, blood pressure and heart rate during a standard cold stress in Australia and Antarctica.在澳大利亚和南极洲进行标准冷应激试验期间的体温、寒战、血压和心率。
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4
Urinary excretion of adrenal steroids, catecholamines and electrolytes in man, before and after acclimatization to cold in Antarctica.人类在适应南极洲寒冷环境前后肾上腺类固醇、儿茶酚胺和电解质的尿排泄情况。
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[CHANGES IN THE CARDIOVASCULAR SYSTEM DURING ACCLIMATIZATION IN INTRACONTINENTAL AREAS OF ANTARCTICA].
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3
Effects of acclimatization to cold baths on men's responses to whole-body cooling in air.冷水浴适应性对男性在空气中全身冷却反应的影响。
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Int J Biometeorol. 1993 Dec;37(4):218-21. doi: 10.1007/BF01387527.
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Urinary excretion of adrenal steroids, catecholamines and electrolytes in man, before and after acclimatization to cold in Antarctica.人类在适应南极洲寒冷环境前后肾上腺类固醇、儿茶酚胺和电解质的尿排泄情况。
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8
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10
Changing cold acclimatization patterns of men living in Antarctica.南极洲男性寒冷适应模式的变化。
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本文引用的文献

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Nutritional factors in cold acclimatization.冷适应中的营养因素。
J Occup Med. 1960 Apr;2:177-87 contd.
2
RESPONSES OF COLD-ACCLIMATIZED MEN TO INFUSED NOREPINEPHRINE.
J Appl Physiol. 1963 Nov;18:1209-12. doi: 10.1152/jappl.1963.18.6.1209.
3
Comparison between seasonal and thermal acclimation in white rats. V. Metabolic and cardiovascular response to noradrenaline.白鼠季节性适应与热适应的比较。V. 对去甲肾上腺素的代谢和心血管反应。
Can J Biochem Physiol. 1961 Dec;39:1829-36.
4
Acclimatization to cold in Antarctica as shown by rectal temperature. Response to a standard cold stress.通过直肠温度显示的在南极洲对寒冷的适应。对标准冷应激的反应。
Nature. 1962 Mar 3;193:886. doi: 10.1038/193886a0.
5
The calorigenic response of cold-acclimated white rats to infused noradrenaline.冷适应大白鼠对注入去甲肾上腺素的产热反应。
Can J Biochem Physiol. 1960 Feb;38:107-14.
6
Thermal and metabolic responses of men in the Antarctic to a standard cold stress.南极男性对标准冷应激的热反应和代谢反应。
J Appl Physiol. 1961 May;16:401-4. doi: 10.1152/jappl.1961.16.3.401.
7
Role of adrenaline and noradrenaline in chemical regulation of heat production.肾上腺素和去甲肾上腺素在产热化学调节中的作用。
Am J Physiol. 1957 Aug;190(2):243-6. doi: 10.1152/ajplegacy.1957.190.2.243.
8
Regulation of heat production in cold-adapted rats.
Proc Soc Exp Biol Med. 1956 Aug-Sep;92(4):845-9. doi: 10.3181/00379727-92-22632.
9
Body temperature, shivering, blood pressure and heart rate during a standard cold stress in Australia and Antarctica.在澳大利亚和南极洲进行标准冷应激试验期间的体温、寒战、血压和心率。
J Physiol. 1966 Sep;186(1):216-32. doi: 10.1113/jphysiol.1966.sp008030.

在南极洲适应寒冷前后，人体对去甲肾上腺素的心血管和代谢反应。

Cardiovascular and metabolic responses to noradrenaline in man, before and after acclimatization to cold in Antarctica.

作者信息

Budd G M, Warhaft N

出版信息

J Physiol. 1966 Sep;186(1):233-42. doi: 10.1113/jphysiol.1966.sp008031.

DOI:10.1113/jphysiol.1966.sp008031
PMID:5914256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1395886/
Abstract
  1. Four men of European descent were infused with noradrenaline at rates of 0.038, 0.075, 0.150 and 0.300 mug/kg.min in Australia, and again after 29 weeks' residence at Mawson, Antarctica. A concurrent study of their responses to whole-body cooling showed that they acclimatized to cold in Antarctica.2. Blood pressure rose and heart rate fell in proportion to the dose of noradrenaline infused. The response was much less after than before acclimatization in three of the four subjects. Subjective effects of the drug decreased in proportion to the decrease in the pressor effect.3. Finger temperature fell in proportion to the dose infused, in three subjects. The response was unchanged or increased after acclimatization.4. Oxygen consumption was initially unaffected by noradrenaline, but after acclimatization it apparently increased in proportion to the dose infused. The increase in pulmonary ventilation during infusion was slightly greater after acclimatization.
摘要

  1. 在澳大利亚，四名欧洲裔男性以0.038、0.075、0.150和0.300微克/千克·分钟的速率输注去甲肾上腺素，在南极洲莫森居住29周后再次进行输注。一项关于他们对全身冷却反应的同期研究表明，他们在南极洲适应了寒冷环境。

  2. 血压升高，心率下降，且与输注的去甲肾上腺素剂量成正比。在四名受试者中的三名，适应后的反应比适应前小得多。药物的主观效应与升压效应的降低成正比。

  3. 在三名受试者中，手指温度与输注剂量成正比下降。适应后反应未变或增强。

  4. 氧耗最初不受去甲肾上腺素影响，但适应后明显与输注剂量成正比增加。输注期间肺通气的增加在适应后略大。