犬吸入氧化亚氮对脑循环及代谢的刺激作用。采用直接法和凯蒂-施密特法同步测量脑血流量进行再确认。

Cerebral circulatory and metabolic stimulation with nitrous oxide in the dog. Reconfirmation by the simultaneous measurement of cerebral blood flow using direct and Kety-Schmidt methods.

作者信息

Oshita S, Ishikawa T, Tokutsu Y, Takeshita H

出版信息

Acta Anaesthesiol Scand. 1979 Apr;23(2):177-81. doi: 10.1111/j.1399-6576.1979.tb01438.x.

DOI:10.1111/j.1399-6576.1979.tb01438.x

Abstract

In both the presence and the absence of nitrous oxide (57%, end-tidal), cerebral blood flow (CBF) was measured by a direct method in dogs, and compared to an indirect method (Kety-Schmidt method), using argon as the tracer. Eighteen comparisons were made in five dogs at flows ranging from 45 to 123 ml per 100 g per minute. There was no systematic difference in CBF between the direct and indirect methods, and the ratio of direct CBF to indirect CBF was 1.03. The cerebral circulatory and metabolic stimulation effect of N2O in the dog was reconfirmed.

摘要

在有和没有氧化亚氮（57%，呼气末）的情况下，通过直接方法在犬类中测量脑血流量（CBF），并与使用氩作为示踪剂的间接方法（Kety-Schmidt法）进行比较。在五只犬类中，于每分钟每100克45至123毫升的血流量范围内进行了18次比较。直接法和间接法测得的CBF之间没有系统性差异，直接CBF与间接CBF的比值为1.03。再次证实了氧化亚氮对犬类脑循环和代谢的刺激作用。