膀胱癌：吸烟、饮品与人工甜味剂。
Bladder cancer: smoking, beverages and artificial sweeteners.
作者信息
Morgan R W, Jain M G
出版信息
Can Med Assoc J. 1974 Nov 16;111(10):1067-70.
Abstract
A matched patient-control study of bladder cancer examined the relationship of the disease to occupation, smoking and intake of tea, coffee, cola, alcohol and artificial sweeteners.There was no association of disease with occupation for these patients. Heavy smoking gave relative risks of 6.37 and 4.36 for men and women respectively; there was evidence of a dose-response relationship. Tea and coffee intake did not increase the risk of disease nor did prolonged use of artificial sweeteners. Alcohol and cola intake increased the relative risk of bladder cancer among male smokers. There is some suggestion that smoking interacts with both alcohol and cola intake in the production of bladder cancer.
摘要
一项针对膀胱癌的配对病例对照研究，考察了该疾病与职业、吸烟以及茶、咖啡、可乐、酒精和人工甜味剂摄入量之间的关系。这些患者的疾病与职业无关。重度吸烟使男性和女性的相对风险分别为6.37和4.36；有证据表明存在剂量反应关系。茶和咖啡的摄入量并未增加患病风险，长期使用人工甜味剂也没有这种影响。酒精和可乐的摄入量增加了男性吸烟者患膀胱癌的相对风险。有迹象表明，在膀胱癌的发生过程中，吸烟与酒精和可乐的摄入量之间存在相互作用。
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