Peyman G A, Zweig K
Am J Ophthalmol. 1979 Apr;87(4):561-6. doi: 10.1016/0002-9394(79)90249-6.
Uncoated intraocular lenses caused extensive corneal endothelial cell damage after in vitro contact (mean, 30.9% cell loss), whereas lenses coated with bovine submaxillary mucin type 1 caused minimal cell loss (mean 4.3%). No observable in vivo toxicity in the eye occurred when 0.1 ml of 3, 6, or 9% solution was injected into the anterior chamber. Mucin-coated lenses can be sterilized by ethylene oxide with no measurable adsorbence into the coating. Scanning electron microscopy confirmed the results from vital staining.
未镀膜的人工晶状体在体外接触后导致广泛的角膜内皮细胞损伤(平均细胞损失率为30.9%),而涂有1型牛颌下粘蛋白的晶状体导致的细胞损失最小(平均为4.3%)。当向前房注射0.1 ml 3%、6%或9%的溶液时,在眼中未观察到体内毒性。粘蛋白涂层的晶状体可用环氧乙烷消毒,涂层中无可测量的吸附现象。扫描电子显微镜证实了活体染色的结果。