Fechner P U, Fechner M U
Br J Ophthalmol. 1983 Apr;67(4):259-63. doi: 10.1136/bjo.67.4.259.
Methylcellulose has been used since 1976 to prevent damage to the corneal endothelium during operations for implantation of intraocular lenses. Originally one drop of a 1% solution was placed on the artificial lens just before its insertion. Later the anterior chamber was completely filled with a 2% solution of methylcellulose before implantation. In this way it is possible to maintain a space between the cornea and iris even if vitreous pressure is present and to operate without risk to the corneal endothelium. This paper demonstrates the safety of the intraocular use of methylcellulose on the basis of over 400 operations. The substance is cheap, universally available, and can be easily prepared for intraocular use.
自1976年以来,甲基纤维素一直被用于在人工晶状体植入手术中防止角膜内皮损伤。最初,在人工晶状体植入前,将一滴1%的溶液滴在人工晶状体上。后来,在植入前,前房被2%的甲基纤维素溶液完全充满。通过这种方式,即使存在玻璃体压力,也能够在角膜和虹膜之间维持一个空间,并且在不对角膜内皮造成风险的情况下进行手术。本文基于400多例手术证明了眼内使用甲基纤维素的安全性。该物质价格便宜,普遍可得,并且可以很容易地制备用于眼内使用。