Gazet J C, Pilkington T R, Kalucy R S, Crisp A H, Day S
Br Med J. 1974 Nov 9;4(5940):311-4. doi: 10.1136/bmj.4.5940.311.
Jejunal bypass operations were performed on 47 grossly obese patients. The results were disappointing in three patients who had a standard "14 in/4 in" Payne and DeWind procedure and therefore a more radical operation was performed, joining four inches (10.2 cm) of proximal jejunum to 10 inches (24.4 cm) of terminal ileum. Two years after the modified operation a mean of 44.2 kg had been lost and the weight tended to stabilize. This weight loss was due mainly to inadequate calorie intake. The appetite became more controlled so that if weight was regained this was small in amount. Metabolic sequelae and their symptoms also settled by two years. The physical, psychological, and social outcome was good. The postoperative period was stormy and required close medical and psychiatric supervision. There were two deaths.
对47名极度肥胖患者实施了空肠旁路手术。采用标准的“14英寸/4英寸”佩恩和德温德手术的3名患者效果不佳，因此实施了更为彻底的手术，将近端空肠4英寸（10.2厘米）与回肠末端10英寸（24.4厘米）相连。改良手术后两年，平均体重减轻了44.2千克，且体重趋于稳定。这种体重减轻主要是由于热量摄入不足。食欲得到了更好的控制，因此即便体重有所恢复，增加的幅度也很小。代谢后遗症及其症状在两年后也得到了缓解。身体、心理和社会方面的结果良好。术后情况不稳定，需要密切的医学和精神科监护。有两例死亡。
