Terkel J, Bridges R S, Sawyer C H
Brain Res. 1979 Jun 22;169(2):369-80. doi: 10.1016/0006-8993(79)91037-0.
In lactating female rats bilateral parasagittal cuts transecting the dorsolateral neural connections of the medial preoptic area (MPOA) abolished nest building and retrieving components of maternal behavior, while crouching and nursing were unaffected. While few animals with these cuts were suckled when presented with pups the prolactin secretion response was undiminished when suckling did occur. Whereas previous studies have demonstrated that extensive surgical separation of the medial preoptic area-anterior hypothalamic continuum from the lateral preoptic area-lateral hypothalamus disrupts all aspects of maternal behavior, the present study has determined more specifically the zone of fibers essential for the active components of maternal behavior, i.e., nest building and retrieving. These fibers appear to enter/leave MPO dorsolaterally beneath the crossing of the anterior commissure in the region of the bed nucleus of the stria terminalis. These neural connections are not the same as those that regulate prolactin secretion in the lactating rat.
在哺乳期雌性大鼠中，双侧矢状旁切口切断内侧视前区（MPOA）的背外侧神经连接，消除了筑巢和找回幼崽等母性行为成分，而蹲伏和哺乳行为不受影响。虽然接受这些切口手术的动物很少有在接触幼崽时进行哺乳的情况，但当确实发生哺乳时，催乳素分泌反应并未减弱。尽管先前的研究表明，内侧视前区 - 下丘脑前部连续体与外侧视前区 - 外侧下丘脑的广泛手术分离会破坏母性行为的所有方面，但本研究更具体地确定了母性行为主动成分（即筑巢和找回幼崽）所必需的纤维区域。这些纤维似乎在终纹床核区域前连合交叉下方从背外侧进入/离开MPO。这些神经连接与调节哺乳期大鼠催乳素分泌的神经连接不同。
