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甘油酯甘油合成途径。

Pathways of glyceride glycerol synthesis.

作者信息

Rognstad R, Clark D G, Katz J

出版信息

Biochem J. 1974 May;140(2):249-51. doi: 10.1042/bj1400249.

Abstract

Isolated rat liver parenchymal cells were incubated for various periods with [U-(14)C,2-(3)H]glycerol and the radioisotopic yields in the major products were determined, as well as the (3)H/(14)C ratios in glyceride glycerol and intracellular glycerol phosphate. Under the conditions used (0.1mm-glycerol+10mm-l-lactate or 10mm-glycerol as substrates), only small differences were found between these (3)H/(14)C ratios. The results suggest a minor role for a pathway of glyceride glycerol synthesis involving reduction of acylated dihydroxyacetone phosphate, under these experimental conditions.

摘要

将分离的大鼠肝脏实质细胞与[U-(14)C,2-(3)H]甘油孵育不同时间,测定主要产物中的放射性同位素产率,以及甘油酯甘油和细胞内甘油磷酸中的(3)H/(14)C 比值。在所使用的条件下(以0.1mmol/L甘油+10mmol/L L-乳酸或10mmol/L甘油作为底物),这些(3)H/(14)C 比值之间仅发现微小差异。结果表明,在这些实验条件下,涉及酰化磷酸二羟丙酮还原的甘油酯甘油合成途径作用较小。

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Pathways of glyceride glycerol synthesis.甘油酯甘油合成途径。
Biochem J. 1974 May;140(2):249-51. doi: 10.1042/bj1400249.

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