Nolewajka A J, Kostuk W J, Rechnitzer P A, Cunningham D A
Circulation. 1979 Jul;60(1):114-21. doi: 10.1161/01.cir.60.1.114.
The effect of exercise on the development of intercoronary collaterals and on left ventricular function is controversial. Twenty male patients (mean age 48 years, range 36-54 years) who had suffered an acute myocardial infarction were randomly allocated to an exercise group (10 patients) and a control group (10 patients). Both groups underwent coronary angiography, left ventricular function studies and myocardial perfusion studies with labeled microspheres, before and after the 7-month experimental period. Both groups had similar extent of disease as measured angiographically and both had mild progression of disease. Neither group showed changes in extent of callateralization, myocardial perfusion or left ventricular function. The exercise group had a significant increase in anginal threshold and a significant (p less than 0.01) decrease in heart rate at a given work load. Exercise, therefore, does not appear to affect progression of disease, myocardial perfusion, extent of collateralization, or left ventricular function in patients with coronary artery disease.
运动对冠状动脉侧支循环发育及左心室功能的影响存在争议。20例急性心肌梗死男性患者（平均年龄48岁，范围36 - 54岁）被随机分为运动组（10例）和对照组（10例）。在7个月的实验期前后，两组均接受了冠状动脉造影、左心室功能研究以及用标记微球进行的心肌灌注研究。两组经血管造影测量的疾病程度相似，且疾病均有轻度进展。两组在侧支循环形成程度、心肌灌注或左心室功能方面均未显示出变化。运动组在给定工作负荷下心绞痛阈值显著升高，心率显著降低（p < 0.01）。因此，运动似乎并不影响冠心病患者的疾病进展、心肌灌注、侧支循环形成程度或左心室功能。
