一种氨基糖苷类2'-N-乙酰化酶。 - Suppr

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A 2'-N-acetylating enzyme of aminoglycosides.

作者信息

Yamaguchi M, Mitsuhashi S, Kobayashi F, Zenda H

出版信息

J Antibiot (Tokyo). 1974 Jul;27(7):507-15. doi: 10.7164/antibiotics.27.507.

DOI:10.7164/antibiotics.27.507

PMID:4457531

Abstract

摘要

相似文献

A 2'-N-acetylating enzyme of aminoglycosides.一种氨基糖苷类2'-N-乙酰化酶。

J Antibiot (Tokyo). 1974 Jul;27(7):507-15. doi: 10.7164/antibiotics.27.507.

[New profile of a resistance to aminoglycosides in Pseudomonas aeruginosa].[铜绿假单胞菌对氨基糖苷类抗生素耐药性的新概况]

Pathol Microbiol (Basel). 1974;40(3):189-90.

Phosphorylation of kanamycin, lividomycin A, amd butirosin B by Providencia stuartii.斯氏普罗威登斯菌对卡那霉素、青紫霉素A和丁胺卡那霉素B的磷酸化作用

Antimicrob Agents Chemother. 1974 Dec;6(6):821-4. doi: 10.1128/AAC.6.6.821.

Aminoglycoside resistance in bacteria medicated by gentamicin acetyltransferase II, an enzyme modifying the 2'-amino group of aminoglycoside antibiotics.由庆大霉素乙酰转移酶II介导的细菌对氨基糖苷类抗生素的耐药性，该酶可修饰氨基糖苷类抗生素的2'-氨基基团。

Biochemistry. 1974 Jan 29;13(3):598-603. doi: 10.1021/bi00700a030.

Inducible expression of an aminoglycoside-acetylating enzyme in Providencia stuartii.在斯氏普罗威登斯菌中氨基糖苷乙酰化酶的可诱导表达。

J Antimicrob Chemother. 1987 Jan;19(1):27-30. doi: 10.1093/jac/19.1.27.

Kanamycin resistance in Providencia stuartii.斯氏普罗威登斯菌中的卡那霉素抗性

J Antimicrob Chemother. 1978 May;4(3):273-8. doi: 10.1093/jac/4.3.273.

Acquired cross resistance to aminoglycosides in gentamicin-sensitive and gentamicin-resistant strains of enterobacteria.在对庆大霉素敏感和耐药的肠杆菌菌株中获得对氨基糖苷类的交叉耐药性。

J Med Microbiol. 1981 May;14(2):171-83. doi: 10.1099/00222615-14-2-171.

[New enzyme mechanism of resistance to aminoglucoside antibiotics].[对氨基糖苷类抗生素耐药的新酶机制]

Ann Biol Clin (Paris). 1973;31(5):353-7.

Antimicrobial effectiveness ofkanamycin, aminosidin, BB-K8, sisomicin, gentamicin and tobramycin combined with carbenicillin or cephalothin against gram-negative rods.卡那霉素、氨基糖苷、BB-K8、西索米星、庆大霉素和妥布霉素联合羧苄青霉素或头孢噻吩对革兰氏阴性杆菌的抗菌效果。

J Med Microbiol. 1974 Nov;7(4):465-72. doi: 10.1099/00222615-7-4-465.

Comparison of the in vitro activities of BB-K8 and three other aminoglycosides against 215 strains of Pseudomonas and Enterobacteriaceae with variable sensitivity to kanamycin and gentamicin.BB-K8与其他三种氨基糖苷类药物对215株对卡那霉素和庆大霉素敏感性各异的假单胞菌属和肠杆菌科细菌的体外活性比较。

Chemotherapy. 1975;21(1):45-51. doi: 10.1159/000221843.

引用本文的文献

Overexpression and characterization of the chromosomal aminoglycoside 2'-N-acetyltransferase of Providencia stuartii.斯氏普罗威登斯菌染色体氨基糖苷2'-N-乙酰基转移酶的过表达及特性分析

Antimicrob Agents Chemother. 2001 Aug;45(8):2238-44. doi: 10.1128/AAC.45.8.2238-2244.2001.

Activation of the 2'-N-acetyltransferase gene [aac(2')-Ia] in Providencia stuartii by an interaction of AarP with the promoter region.通过AarP与启动子区域的相互作用激活斯氏普罗威登斯菌中的2'-N-乙酰转移酶基因[aac(2')-Ia] 。

Antimicrob Agents Chemother. 1999 Jul;43(7):1769-72. doi: 10.1128/AAC.43.7.1769.

Mutations in aarE, the ubiA homolog of Providencia stuartii, result in high-level aminoglycoside resistance and reduced expression of the chromosomal aminoglycoside 2'-N-acetyltransferase.斯氏普罗威登斯菌的泛醌生物合成酶A同源物aarE发生突变，会导致高水平氨基糖苷耐药性，并使染色体氨基糖苷2'-N-乙酰转移酶的表达降低。

Antimicrob Agents Chemother. 1998 Apr;42(4):959-62. doi: 10.1128/AAC.42.4.959.

Identification and characterization of aarF, a locus required for production of ubiquinone in Providencia stuartii and Escherichia coli and for expression of 2'-N-acetyltransferase in P. stuartii.鉴定和表征aarF，这是一个在斯氏普罗威登斯菌和大肠杆菌中参与泛醌合成以及在斯氏普罗威登斯菌中参与2'-N-乙酰转移酶表达所必需的基因座。

J Bacteriol. 1998 Jan;180(1):128-35. doi: 10.1128/JB.180.1.128-135.1998.

An extracellular factor regulating expression of the chromosomal aminoglycoside 2'-N-acetyltransferase of Providencia stuartii.一种调节斯氏普罗威登斯菌染色体氨基糖苷2'-N-乙酰基转移酶表达的细胞外因子。

Antimicrob Agents Chemother. 1997 Aug;41(8):1749-54. doi: 10.1128/AAC.41.8.1749.

Characterization of gentamicin 2'-N-acetyltransferase from Providencia stuartii: its use of peptidoglycan metabolites for acetylation of both aminoglycosides and peptidoglycan.斯氏普罗威登斯菌庆大霉素2'-N-乙酰基转移酶的特性：其利用肽聚糖代谢产物对氨基糖苷类和肽聚糖进行乙酰化作用。

J Bacteriol. 1997 Jul;179(13):4106-14. doi: 10.1128/jb.179.13.4106-4114.1997.

aarC, an essential gene involved in density-dependent regulation of the 2'-N-acetyltransferase in Providencia stuartii.aarC，一个参与斯氏普罗威登斯菌中2'-N-乙酰转移酶密度依赖性调控的必需基因。

J Bacteriol. 1997 Apr;179(7):2267-73. doi: 10.1128/jb.179.7.2267-2273.1997.

Characterization and transcriptional regulation of the 2'-N-acetyltransferase gene from Providencia stuartii.斯氏普罗威登斯菌2'-N-乙酰基转移酶基因的特性与转录调控

J Bacteriol. 1993 Oct;175(20):6492-8. doi: 10.1128/jb.175.20.6492-6498.1993.

Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.氨基糖苷类耐药基因的分子遗传学及氨基糖苷类修饰酶的家族关系。

Microbiol Rev. 1993 Mar;57(1):138-63. doi: 10.1128/mr.57.1.138-163.1993.

Identification and analysis of aarP, a transcriptional activator of the 2'-N-acetyltransferase in Providencia stuartii.斯氏普罗威登斯菌中2'-N-乙酰转移酶转录激活因子aarP的鉴定与分析。

J Bacteriol. 1995 Jun;177(12):3407-13. doi: 10.1128/jb.177.12.3407-3413.1995.

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