Kiricuta I, Frenkel Z, Munteanu S
Arch Geschwulstforsch. 1974;44(3):260-6.
Urinary outpout of oestrogens and 17-ketosteroids were estimated in 200 women with breast cancer; 60 of them were cases with rapid evolution (malignant evolutive push). The majority of cases analysed had abnormal hormonal levels, especially of oestrogens. The average oestrogenic levels are higher than the normal values; the highest values correspond to the most severe and rapidly evolutive type of breast cancer, the inflammatory breast carcinoma. In the patients without evolutive push, the proportion of cases with absolute or relative hypooestrogeny is approximately equal toor exceeds the proportion of hyperoestrogenic cases. In the presence of the evolutive push and especially of his most severe type, inflammatory carcinoma, the cases with hyperoestrogeny, both absolute and relative, by hypoandrogeny, are dominant. The proportion of cases with higher 17-ketosteroid urinary outputs than the normal mean is greater in the patients without evolutive push, while in those with evolutive push, the majority of cases have lower values of 17-ketosteroids than the normal mean.
对200例乳腺癌女性患者的雌激素和17 - 酮类固醇尿排泄量进行了评估；其中60例为快速进展型（恶性进展性侵袭）病例。大多数分析病例的激素水平异常，尤其是雌激素。雌激素平均水平高于正常值；最高值对应最严重且进展迅速的乳腺癌类型，即炎性乳腺癌。在无进展性侵袭的患者中，绝对或相对雌激素缺乏病例的比例约等于或超过雌激素过多病例的比例。在存在进展性侵袭尤其是其最严重类型炎性癌的情况下，绝对和相对雌激素过多伴雄激素缺乏的病例占主导。17 - 酮类固醇尿排泄量高于正常均值的病例比例在无进展性侵袭的患者中更大，而在有进展性侵袭的患者中，大多数病例的17 - 酮类固醇值低于正常均值。
